McGuffin Peter, Southwick Linda
MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's Colllege, London, De Crespigny Park, UK.
Aust N Z J Psychiatry. 2003 Dec;37(6):657-61. doi: 10.1080/j.1440-1614.2003.01266.x.
To discuss the impact of Watson and Crick's double helix discovery on the field of psychiatry.
Psychiatric research studies using molecular genetic techniques are summarized. The implications of these findings in terms of our understanding and treatment of mental illness are discussed.
There now exists growing evidence of candidate gene sites for a variety of psychiatric disorders ranging from schizophrenia to reading disability.
The field of psychiatric genetics has become one of the most vital and productive areas of psychiatric research. New findings are continually coming to light, bringing us ever closer to understanding these complex disorders at a molecular level. Such knowledge could lead to improved drug treatments, screening of at-risk individuals and even a reduction in the stigma attached to psychiatric disorders.
探讨沃森和克里克的双螺旋发现对精神病学领域的影响。
总结使用分子遗传学技术的精神病学研究。讨论这些发现在我们对精神疾病的理解和治疗方面的意义。
现在有越来越多的证据表明，从精神分裂症到阅读障碍等各种精神疾病都存在候选基因位点。
精神病遗传学领域已成为精神病学研究中最重要、最有成果的领域之一。新发现不断涌现，使我们在分子水平上对这些复杂疾病的理解越来越近。这样的知识可能会带来更好的药物治疗、对高危个体的筛查，甚至减少与精神疾病相关的耻辱感。
