Kawanishi K, Ueda H, Nagase M, Ofuji T
Acta Med Okayama. 1977 Oct;31(5):319-24.
Plasma postheparin lipolytic activity (PHLA) was measured on 50 patients with systemic lupus erythematosus (SLE). Plasma PHLA was significantly decreased in SLE patients. This decrease was most striking in the acute phase of the disease. There was a close relationship between decreased PHLA and immunologic factors indicative of the acute phase of SLE. These immunologic factors included shaggy antinuclear antibody pattern, low serum complement titer, high DNA antibody titer, mixed cryoglobulin and lumpy glomerular pattern by immunofluorescent staining.
对50例系统性红斑狼疮(SLE)患者测定了血浆肝素后脂解活性(PHLA)。SLE患者的血浆PHLA显著降低。这种降低在疾病急性期最为明显。PHLA降低与提示SLE急性期的免疫因素之间存在密切关系。这些免疫因素包括粗糙型抗核抗体模式、低血清补体滴度、高DNA抗体滴度、混合冷球蛋白以及免疫荧光染色显示的颗粒状肾小球模式。