Analgesic issues in palliative care, furthering our understanding of pain, the stability and cost of opioid infusion therapy, and opioid effectiveness doses in nociceptive and neuropathic pain.

Literature relating to analgesic issues, pain mechanisms and management, costs of opioid infusions, and the opioids dosing for nociceptive and neuropathic pain are reviewed in the context of palliative care.