Dockery D W, Schwartz J, Spengler J D
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115.
Environ Res. 1992 Dec;59(2):362-73. doi: 10.1016/s0013-9351(05)80042-8.
The association between total daily mortality and air pollution was investigated for a 1-year period (September 1985 through August 1986) in St. Louis and in the counties in eastern Tennessee surrounding Kingston/Harriman. The purpose of this study was to evaluate the relative importance of various measures of particulate and gaseous air pollution as predictors of daily mortality. Concentrations of inhalable particles (PM10), fine particles (PM2.5), the elemental composition of these particles, and aerosols acidity were measured daily during the period of study. The effect of each air pollutant on daily mortality was estimated after controlling for meteorologic and seasonal influences. Total mortality in St. Louis was found to increase 16% (95% CI-1 to 33%) for each 100 micrograms/m3 increase in PM10, and by 17% (95% CI-12 to 57%) in eastern Tennessee. Positive but progressively weaker associations were found with PM2.5, sulfate, and aerosol acidity concentrations in both communities. Associations with gaseous pollutants--sulfur dioxide, nitrogen dioxide, and ozone--were all far from statistical significance. Because of the short monitoring period for daily particulate air pollution, the power of this study to detect associations was limited. Nevertheless, statistically significant associations with PM10 were found in St. Louis, and, more importantly, the estimated effects were consistent between the two communities studied and with other reported analyses of the effects of particles on daily mortality. These data suggest that the acidity of particles is not as important in associations with daily mortality as the mass concentrations of particles.
在圣路易斯以及田纳西州东部金斯敦/哈里曼周边各县,对1985年9月至1986年8月这1年期间每日总死亡率与空气污染之间的关联进行了调查。本研究的目的是评估各种颗粒物和气态空气污染指标作为每日死亡率预测指标的相对重要性。在研究期间,每天测量可吸入颗粒物(PM10)、细颗粒物(PM2.5)的浓度、这些颗粒物的元素组成以及气溶胶酸度。在控制了气象和季节影响后,估计了每种空气污染物对每日死亡率的影响。在圣路易斯,PM10每增加100微克/立方米,总死亡率增加16%(95%可信区间为-1%至33%);在田纳西州东部,这一增幅为17%(95%可信区间为-12%至57%)。在两个社区中,均发现与PM2.5、硫酸盐和气溶胶酸度浓度呈正相关,但相关性逐渐减弱。与气态污染物——二氧化硫、二氧化氮和臭氧——的相关性均远未达到统计学显著性。由于每日颗粒物空气污染的监测期较短,本研究检测关联的能力有限。尽管如此,在圣路易斯发现了与PM10的统计学显著关联,更重要的是,在两个研究社区之间以及与其他关于颗粒物对每日死亡率影响的报道分析中,估计的影响是一致的。这些数据表明,在与每日死亡率的关联中,颗粒物的酸度不如颗粒物的质量浓度重要。