Egron David, Périgaud Christian, Gosselin Gilles, Aubertin Anne-Marie, Faraj Abdesslem, Sélouane Majid, Postel Denis, Len Christophe
UMR 5625 CNRS-UM II, Université Montpellier II, cc 008, place E. Bataillon, 34095 Cedex 5, Montpellier, France.
Bioorg Med Chem Lett. 2003 Dec 15;13(24):4473-5. doi: 10.1016/j.bmcl.2003.09.031.
The detailed study of the 1,3-dihydrobenzo[c]furan derivative of thymine is reported. The lack of anti-HIV activity of this compound in cell culture experiments is shown to be related to the inability of the corresponding 5'-triphosphate derivative to interact efficiently with the reverse transcriptase.
