Gerstel Ulrich, Römling Ute
Microbiology and Tumorbiology Center (MTC), Karolinska Institute, Stockholm, Sweden.
Res Microbiol. 2003 Dec;154(10):659-67. doi: 10.1016/j.resmic.2003.08.005.
Expression of cellulose and curli fimbriae in Salmonella typhimurium is dependent on the transcriptional regulator CsgD. Transcription of csgD itself is influenced by a variety of regulatory stimuli. Complex nucleoprotein arrangements modulate the transcriptional activity of csgD and trigger the transition between the planktonic status and biofilm formation.
鼠伤寒沙门氏菌中纤维素和卷曲菌毛的表达依赖于转录调节因子CsgD。csgD自身的转录受多种调节刺激的影响。复杂的核蛋白排列调节csgD的转录活性,并触发浮游状态和生物膜形成之间的转变。