哺乳动物中鼠白血病病毒限制的特征描述。
Characterization of murine leukemia virus restriction in mammals.
作者信息
Besnier Caroline, Ylinen Laura, Strange Benjamin, Lister Adrian, Takeuchi Yasuhiro, Goff Stephen P, Towers Greg J
机构信息
Wohl Virion Centre, Department of Immunology and Molecular Pathology, University College London, London W1T 4JF, United Kingdom.
出版信息
J Virol. 2003 Dec;77(24):13403-6. doi: 10.1128/jvi.77.24.13403-13406.2003.
Abstract
Restriction of murine leukemia virus (MLV) was examined in cells from a range of mammals. All nonmurine restrictions were saturable blocks to N-tropic MLV infection, and several were prior to reverse transcription. We demonstrate restriction in cells from bat and show that if we express the murine restriction factor Fv1 in human cells, then Fv1, not the human host, defines the stage at which infection is blocked.
摘要
在一系列哺乳动物的细胞中检测了对鼠白血病病毒（MLV）的限制作用。所有非鼠类的限制都是对N-嗜性MLV感染的饱和阻断，其中一些发生在逆转录之前。我们证明了蝙蝠细胞中的限制作用，并表明如果我们在人类细胞中表达鼠类限制因子Fv1，那么定义感染被阻断阶段的是Fv1，而非人类宿主。
相似文献
1
Characterization of murine leukemia virus restriction in mammals.
J Virol. 2003 Dec;77(24):13403-6. doi: 10.1128/jvi.77.24.13403-13406.2003.
2
Expression levels of Fv1: effects on retroviral restriction specificities.
Retrovirology. 2016 Jun 24;13(1):42. doi: 10.1186/s12977-016-0276-7.
3
The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-tropic murine leukemia virus capsid.
J Virol. 2007 Mar;81(5):2138-48. doi: 10.1128/JVI.02318-06. Epub 2006 Nov 29.
4
Generation and characterization of a stable full-length ecotropic murine leukemia virus molecular clone that produces novel phenotypes to Fv1 restriction.
J Microbiol Biotechnol. 2008 Apr;18(4):799-804.
5
Fv1-like restriction of N-tropic replication-competent murine leukaemia viruses in mCAT-1-expressing human cells.
J Gen Virol. 2002 Feb;83(Pt 2):439-442. doi: 10.1099/0022-1317-83-2-439.
6
A conserved mechanism of retrovirus restriction in mammals.
Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12295-9. doi: 10.1073/pnas.200286297.
7
Complex determinants within the Moloney murine leukemia virus capsid modulate susceptibility of the virus to Fv1 and Ref1-mediated restriction.
Virology. 2007 Jul 5;363(2):245-55. doi: 10.1016/j.virol.2006.09.048. Epub 2007 Mar 6.
8
Use of a transient assay for studying the genetic determinants of Fv1 restriction.
J Virol. 2000 Aug;74(16):7422-30. doi: 10.1128/jvi.74.16.7422-7430.2000.
9
Abrogation of Ref1 retrovirus restriction in human cells.
J Virol. 2002 Mar;76(5):2548-50. doi: 10.1128/jvi.76.5.2548-2550.2002.
10
Characterization of producer cell-dependent restriction of murine leukemia virus replication.
J Virol. 2002 Jul;76(13):6609-17. doi: 10.1128/jvi.76.13.6609-6617.2002.
引用本文的文献
1
Human Adaptation of Ebola Virus during the West African Outbreak.
Cell. 2016 Nov 3;167(4):1079-1087.e5. doi: 10.1016/j.cell.2016.10.013.
2
Effect of Cocaine on HIV Infection and Inflammasome Gene Expression Profile in HIV Infected Macrophages.
Sci Rep. 2016 Jun 20;6:27864. doi: 10.1038/srep27864.
3
The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion.
Retrovirology. 2016 Mar 22;13:19. doi: 10.1186/s12977-016-0253-1.
4
TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription.
EMBO J. 2015 Aug 4;34(15):2078-95. doi: 10.15252/embj.201490361. Epub 2015 Jun 22.
5
Postentry restriction of Mason-Pfizer monkey virus in mouse cells.
J Virol. 2015 Mar;89(5):2813-9. doi: 10.1128/JVI.03051-14. Epub 2014 Dec 24.
6
An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence.
BMC Genomics. 2011 Jul 8;12:355. doi: 10.1186/1471-2164-12-355.
7
Primate and feline lentiviruses in current intrinsic immunity research: the cat is back.
Vet Immunol Immunopathol. 2011 Oct 15;143(3-4):215-20. doi: 10.1016/j.vetimm.2011.06.014. Epub 2011 Jun 12.
8
Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus.
J Virol. 2011 Aug;85(16):8116-32. doi: 10.1128/JVI.00341-11. Epub 2011 Jun 15.
9
SUMO-interacting motifs of human TRIM5α are important for antiviral activity.
PLoS Pathog. 2011 Apr;7(4):e1002019. doi: 10.1371/journal.ppat.1002019. Epub 2011 Apr 7.
10
Activation of nuclear factor-kappa B signalling promotes cellular senescence.
Oncogene. 2011 May 19;30(20):2356-66. doi: 10.1038/onc.2010.611. Epub 2011 Jan 17.
本文引用的文献
1
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors.
Nat Med. 2003 Sep;9(9):1138-43. doi: 10.1038/nm910. Epub 2003 Aug 3.
2
Restriction factors: a defense against retroviral infection.
Trends Microbiol. 2003 Jun;11(6):286-91. doi: 10.1016/s0966-842x(03)00123-9.
3
Restriction of multiple divergent retroviruses by Lv1 and Ref1.
EMBO J. 2003 Feb 3;22(3):385-94. doi: 10.1093/emboj/cdg042.
4
A dominant block to HIV-1 replication at reverse transcription in simian cells.
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13843-8. doi: 10.1073/pnas.212400099. Epub 2002 Oct 4.
5
Restriction of lentivirus in monkeys.
Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11920-5. doi: 10.1073/pnas.172384599. Epub 2002 Aug 1.
6
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism.
Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11914-9. doi: 10.1073/pnas.162299499. Epub 2002 Aug 1.
7
Abrogation of Ref1 retrovirus restriction in human cells.
J Virol. 2002 Mar;76(5):2548-50. doi: 10.1128/jvi.76.5.2548-2550.2002.
8
Molecular phylogenetics and the origins of placental mammals.
Nature. 2001 Feb 1;409(6820):614-8. doi: 10.1038/35054550.
9
A conserved mechanism of retrovirus restriction in mammals.
Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12295-9. doi: 10.1073/pnas.200286297.
10
Use of a transient assay for studying the genetic determinants of Fv1 restriction.
J Virol. 2000 Aug;74(16):7422-30. doi: 10.1128/jvi.74.16.7422-7430.2000.
Zotero 插件