Weissenbacher Mercedes, Rossi Diana, Radulich Graciela, Sosa-Estáni Sergio, Vila Marcelo, Vivas Enrique, Avila María M, Cuchi Paloma, Rey Jorge, Peralta Liliana Martínez
Centro Nacional de Referencia para el SIDA, Facultad de Medicina, Buenos Aires, Argentina.
Clin Infect Dis. 2003 Dec 15;37 Suppl 5:S348-52. doi: 10.1086/377560.
Injection drug use is the main mechanism of human immunodeficiency virus (HIV) transmission in Argentina (40% of reported AIDS cases in Argentina). This study was conducted among street-recruited injection drug users (IDUs) from Buenos Aires, with the aim of estimating seroprevalence and coinfection of HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), and human T-lymphotropic viruses (HTLVs). A total of 174 volunteers participated in this study; 137 were men (78.7% of volunteers). The average age of the participants was 30 years. Only 64 of participants (37%) had no viral infection, whereas 110 (63%) were infected with > or =1 viruses. Seroprevalences were 44.3% for HIV, 54.6% for HCV, 42.5% for HBV, 2.3% for HTLV-I, and 14.5% for HTLV-II. Among the 77 HIV-infected persons, only 6.5% (5 persons) were not coinfected with other viruses; 88.3% (68) were coinfected with HCV and 68.8% (53) were coinfected with HBV. We demonstrated the existence of multiple viral infections with a high rate of prevalence in IDUs in Buenos Aires, Argentina.
注射吸毒是阿根廷人类免疫缺陷病毒（HIV）传播的主要途径（占阿根廷报告艾滋病病例的40%）。本研究在布宜诺斯艾利斯街头招募的注射吸毒者（IDU）中开展，旨在评估HIV、乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）和人类嗜T淋巴细胞病毒（HTLV）的血清学阳性率及合并感染情况。共有174名志愿者参与了本研究；其中137名男性（占志愿者的78.7%）。参与者的平均年龄为30岁。只有64名参与者（37%）没有病毒感染，而110名（63%）感染了≥1种病毒。HIV的血清学阳性率为44.3%，HCV为54.6%，HBV为42.5%，HTLV-I为2.3%，HTLV-II为14.5%。在77名HIV感染者中，只有6.5%（5人）未合并感染其他病毒；88.3%（68人）合并感染HCV，68.8%（53人）合并感染HBV。我们证实了在阿根廷布宜诺斯艾利斯的注射吸毒者中存在多种病毒感染且感染率很高。
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