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经皮消融和酒精注射治疗骨样骨瘤

Percutaneous destruction and alcoholisation for the management of osteoid osteoma.

作者信息

el-Mowafi Hani, Refaat Hesham, Kotb Samir

机构信息

Mansoura University Hospital, 35516 Mansoura, Egypt.

出版信息

Acta Orthop Belg. 2003 Oct;69(5):447-51.

Abstract

Osteoid osteoma (OO) is a small, self-limiting, benign osteogenic tumour. Successful treatment of OO requires complete resection or destruction of the nidus. Surgery, which consists of en bloc excision of the nidus, followed by internal fixation, bone grafting, or both, is successful in almost all cases. In a small percentage of cases the nidus may be missed at surgery, resulting in a failed procedure. The aim of this study was to evaluate the results of percutaneous destruction and alcoholisation as a treatment of OO. Fifteen patients with an osteoid osteoma (10 males, 5 females) were treated in the Oncology Unit, Orthopaedic Department, Mansoura University Hospital. Three OOs were localised in the humerus, 5 in the femur, 6 in the tibia and fibula, and one in the talus. All patients underwent destruction of the nidus by determining the nidus by CT, drilling with a cannulated drill bit, curretting with a speed burr and injecting ethanol. The nidus completely disappeared on the postoperative CT-scan. The average follow-up period was 19 months (6-24 months). There were no postoperative complications. This technique for the treatment of OO is minimally invasive, safe, simple, and cost effective. It allows an early return to normal activities. The procedure is particularly useful for a lesion located deep in the skeleton, which would require an extensive approach with conventional surgery.

摘要

骨样骨瘤(OO)是一种小型、自限性的良性成骨性肿瘤。成功治疗骨样骨瘤需要完全切除或破坏瘤巢。手术包括整块切除瘤巢,随后进行内固定、骨移植或两者同时进行,几乎在所有病例中都能成功。在一小部分病例中,手术时可能会遗漏瘤巢,导致手术失败。本研究的目的是评估经皮破坏和乙醇注射治疗骨样骨瘤的效果。15例骨样骨瘤患者(10例男性,5例女性)在曼苏拉大学医院骨科肿瘤科接受治疗。3例骨样骨瘤位于肱骨,5例位于股骨,6例位于胫腓骨,1例位于距骨。所有患者均通过CT确定瘤巢、用空心钻头钻孔、用高速磨钻刮除并注射乙醇来破坏瘤巢。术后CT扫描显示瘤巢完全消失。平均随访期为19个月(6 - 24个月)。无术后并发症。这种治疗骨样骨瘤的技术微创、安全、简单且具有成本效益。它能使患者早日恢复正常活动。该手术对于位于骨骼深处的病变特别有用,而传统手术对此需要广泛的手术入路。

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