Tsujino I, Betsuyaku T, Inaba S, Yoshikawa T, Terai T
First Department of Medicine, Obihiro Kosei Hospital, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Oct;30(10):1864-8.
A 58-year-old woman was admitted complaining of dry cough and exertional dyspnea. Physical findings, chest X-ray films, chest CT scan and respiratory function tests were suggestive of interstitial pneumonia. Transbronchial lung biopsy showed specific findings of hypersensitivity pneumonitis. As a result of positive provocation test using her home humidifier, a diagnosis of humidifier lung was made. Many microorganisms including Flavobacterium meningosepticum were cultured from the water left in the humidifier for one week. As both complement fixation test and precipitation test were positive to humidifier water and to extract of Flavobacterium meningosepticum, the humidifier and Flavobacterium meningosepticum were suggested to be causative in this case.
一名58岁女性因干咳和劳力性呼吸困难入院。体格检查、胸部X光片、胸部CT扫描及呼吸功能测试均提示间质性肺炎。经支气管肺活检显示了过敏性肺炎的特异性表现。因使用家中加湿器进行激发试验呈阳性,诊断为加湿器肺。从加湿器中留存一周的水中培养出包括脑膜败血黄杆菌在内的多种微生物。由于补体结合试验和沉淀试验对加湿器水及脑膜败血黄杆菌提取物均呈阳性,提示该病例中加湿器及脑膜败血黄杆菌为病因。