Wang Wei, Huang Yong, Zhou Wan-xin, Qiao Lei, Huang Jian-hui, Hu Xin-ai, Yu Zhen, Liu Qing-hua, Wu Zheng-lai
Department of Preventive Care, Dongcheng District Health Bureau, Beijing 100007, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2003 Oct;25(5):533-8.
To describe epidemiological characteristics of an outbreak of severe acute respiratory syndrome (SRAS) in Dongcheng District, Beijing during March to June 2003.
Data of SARS cases notified from Dongcheng District Center for Disease Control and Prevention (CDC) and supplemented by other channels were collected. All data were input into dataset files by Microsoft Excel-2000 software and analyzed with SPSS version 10.0 software.
Totally, 572 cases notified were collected during this period in Dongcheng District, Beijing, and 99 of them were excluded from SARS, because of diagnosis of common cold, pneumonia, measles, or rubella, etc. Actually, 473 SARS cases were analyzed. Attack rate of SARS in permanent residents of Dongcheng was 28.3 per 100,000. Forty-one of them died, with a case-fatality ratio of 8.7%. Outbreak of SARS in Dongcheng District started on March 14, with a peak during mid- and late April, and dropped from May 5, 2003. Persons were all susceptible to SARS, with the highest proportion at ages of 20-50 years, which accounted for 68.7% of the total cases. Average age of the patients at their onset was 40.7 years. No gender difference in SARS cases was found. Number of SARS cases in health care workers (HCWs) accounted for 18.0% and that in the retired persons accounted for 15.4% of the total cases. Cases occurred in all 10 sub-districts of Dongcheng. Totally, 230 of the 572 notified cases (40.2%) hospitalized at local hospitals under the jurisdiction of Dongcheng District. Eighteen of 85 cases of SARS occurred in health care workers of local hospitals, accounting for 4.5% of the total number of health care workers working at the wards caring for SARS patients or at fever clinics. There were 34.7% of SARS cases without any contact histories before their onset. Familial aggregation phenomena were observed in 41.8% of the cases and 18.1% of households. And, 7.4% (attack rate) in those exposed to SARS cases suffered the illness during the periods of quarantine.
SARS appeared outbreak in Dongcheng District, Beijing during March to June 2003. People were all susceptible to SARS, which mainly threatened the young adults and the middle-aged, as well as health care workers and the retired workers. Main mode of transmission was exposure to SARS patients in a near distance at hospitals or families. Prevention and control of SARS should be focused on early isolation of patients and quarantine for the contacts. Current available measures to prevent and control SARS proved effective.
描述2003年3月至6月北京市东城区严重急性呼吸综合征(SARS)疫情的流行病学特征。
收集东城区疾病预防控制中心(CDC)报告并经其他渠道补充的SARS病例资料。所有数据通过Microsoft Excel - 2000软件录入数据集文件,并使用SPSS 10.0软件进行分析。
在此期间,北京市东城区共收集到572例报告病例,其中99例因诊断为普通感冒、肺炎、麻疹或风疹等被排除SARS诊断,实际分析SARS病例473例。东城区常住人口SARS罹患率为28.3/10万。其中41例死亡,病死率为8.7%。东城区SARS疫情于3月14日开始,4月中下旬达到高峰,自2003年5月5日起下降。人群对SARS普遍易感,20 - 50岁年龄段比例最高,占总病例数的68.7%。患者发病时平均年龄为40.7岁。SARS病例无性别差异。医护人员中的SARS病例数占总病例数的18.0%,退休人员中的病例数占15.4%。病例发生在东城区所有10个街道。572例报告病例中共有230例(40.2%)在东城区辖区内的当地医院住院。当地医院的85例SARS病例中有18例发生在医护人员中,占在收治SARS患者病房或发热门诊工作的医护人员总数的4.5%。34.7%的SARS病例发病前无任何接触史。41.8%的病例和18.1%的家庭观察到家庭聚集现象。在隔离期间,接触SARS病例者中有7.4%(罹患率)发病。
2003年3月至6月北京市东城区出现SARS疫情。人群对SARS普遍易感,主要威胁青壮年及医护人员和退休人员。主要传播方式为在医院或家庭近距离接触SARS患者。SARS防控应重点在于早期隔离患者及对密切接触者进行检疫。目前现有的SARS防控措施证明是有效的。