Wang Cheng, Dun Zhe, Zhan Si-yan, Sun Pei-yuan, Liu Yan, Cao Guang-wen, Qin An-li, Dong Shu-lan, Wang Bing-cai
Haidian Center for Disease Control and Prevention, Beijing 100086, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2003 Jul;24(7):561-4.
To analyze epidemiological features of severe acute respiratory syndrome (SARS) in Haidian district, Beijing.
Each SARS case was interviewed by trained investigator using standardized questionnaire followed a descriptive analysis.
Four hundred and three SARS cases were identified and 27 of them died from March 18 and May 31, 2003. The incidence rate of SARS was 18.0/100,000 with case fatality rate as 6.7% in Haidian district, Beijing. Seventy-four percent of patients were adults with higher risk in age group of 20 - 29 year. SARS patients were scattered around in 32 out of 33 streets and villages in this district. The disease appeared to be sporadic but the case of outbreaks in family or university only seen in three streets. The course of SARS epidemic in this district could be divided into three phases: initial-which last for days, peak-21 days and then rapid decline-for 26 days. Number of patients having had a history of close contact to other SARS were gradually decreasing along with the process of the epidemics (trend chi(2) = 8.800, P = 0.003). Seventy-two point seven percent of the SARS cases had been exposed to the injection in the hospital settings. When the epidemics came to a rapid decline, 85.7% of the patients diagnosed during that period could be traced down to have had the history of contacting SARS cases within their own families. The distribution of occupation was also showed significantly different in the three respective stages (chi(2) = 36.41, P < 0.01). Among the patients who could not be identified as having confirmed contact history, 26.6% having had outward activities and 47.6% of them visited hospitals, especially during the peak stage.
The intensity of SARS epidemic among the residents of Haidian district was recognized as similar to the other parts of Beijing. Nosocomial infection in hospital settings was most important cause responsible for the transmission of SARS in this district.
分析北京市海淀区严重急性呼吸综合征（SARS）的流行病学特征。
由经过培训的调查员使用标准化问卷对每例SARS病例进行访谈，随后进行描述性分析。
2003年3月18日至5月31日期间，共确诊403例SARS病例，其中27例死亡。北京市海淀区SARS发病率为18.0/10万，病死率为6.7%。74%的患者为成年人，20 - 29岁年龄组风险较高。SARS患者分布在该地区33个街道和村庄中的32个。该病似乎呈散发性，但仅在3个街道出现家庭或大学内的暴发病例。该地区SARS疫情过程可分为三个阶段：初期持续数天，高峰期21天，随后快速下降期26天。随着疫情发展，有其他SARS密切接触史的患者数量逐渐减少（趋势χ² = 8.800，P = 0.003）。72.7%的SARS病例曾在医院接受注射。当疫情快速下降时，该时期确诊的患者中85.7%可追溯到有家庭内接触SARS病例的病史。职业分布在三个不同阶段也显示出显著差异（χ² = 36.41，P < 0.01）。在无法确定有确诊接触史的患者中，26.6%有外出活动，其中47.6%去过医院，尤其是在高峰期。
海淀区居民中SARS疫情强度与北京市其他地区相似。医院内的医院感染是该地区SARS传播的最重要原因。
