Marlow Scott P, Stoller James K
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Respir Care. 2003 Dec;48(12):1238-54; discussion 1254-6.
Cigarette smoking is the primary cause of chronic obstructive pulmonary disease, and smoking cessation is the most effective means of stopping the progression of chronic obstructive pulmonary disease. Worldwide, approximately a billion people smoke cigarettes and 80% reside in low-income and middle-income countries. Though in the United States there has been a substantial decline in cigarette smoking since 1964, when the Surgeon General's report first reviewed smoking, smoking remains widespread in the United States today (about 23% of the population in 2001). Nicotine is addictive, but there are now effective drugs and behavioral interventions to assist people to overcome the addiction. Available evidence shows that smoking cessation can be helped with counseling, nicotine replacement, and bupropion. Less-studied interventions, including hypnosis, acupuncture, aversive therapy, exercise, lobeline, anxiolytics, mecamylamine, opioid agonists, and silver acetate, have assisted some people in smoking cessation, but none of those interventions has strong research evidence of efficacy. To promote smoking cessation, physicians should discuss with their smoking patients "relevance, risk, rewards, roadblocks, and repetition," and with patients who are willing to attempt to quit, physicians should use the 5-step system of "ask, advise, assess, assist, and arrange." An ideal smoking cessation program is individualized, accounting for the reasons the person smokes, the environment in which smoking occurs, available resources to quit, and individual preferences about how to quit. The clinician should bear in mind that quitting smoking can be very difficult, so it is important to be patient and persistent in developing, implementing, and adjusting each patient's smoking-cessation program. One of the most effective behavioral interventions is advice from a health care professional; it seems not to matter whether the advice is from a doctor, respiratory therapist, nurse, or other clinician, so smoking cessation should be encouraged by multiple clinicians. However, since respiratory therapists interact with smokers frequently, we believe it is particularly important for respiratory therapists to show leadership in implementing smoking cessation.
吸烟是慢性阻塞性肺疾病的主要病因,戒烟是阻止慢性阻塞性肺疾病进展的最有效手段。在全球范围内,约有10亿人吸烟,其中80%居住在低收入和中等收入国家。尽管自1964年美国卫生局局长首次发布关于吸烟的报告以来,美国的吸烟率已大幅下降,但吸烟在美国如今仍然很普遍(2001年约占总人口的23%)。尼古丁具有成瘾性,但现在有有效的药物和行为干预措施来帮助人们克服成瘾问题。现有证据表明,咨询、尼古丁替代疗法和安非他酮有助于戒烟。包括催眠、针灸、厌恶疗法、运动、洛贝林、抗焦虑药、美加明、阿片类激动剂和醋酸银等研究较少的干预措施,已帮助一些人戒烟,但这些干预措施均缺乏有力的疗效研究证据。为促进戒烟,医生应与吸烟患者讨论“相关性、风险、回报、障碍和重复”,对于愿意尝试戒烟的患者,医生应采用“询问、建议、评估、协助和安排”的五步系统。理想的戒烟计划应因人而异,考虑个人吸烟的原因、吸烟的环境、可用的戒烟资源以及个人对戒烟方式的偏好。临床医生应牢记,戒烟可能非常困难,因此在制定、实施和调整每位患者的戒烟计划时,耐心和坚持很重要。最有效的行为干预措施之一是来自医疗保健专业人员的建议;建议来自医生、呼吸治疗师、护士还是其他临床医生似乎并不重要, 因此应由多名临床医生鼓励戒烟。然而,由于呼吸治疗师经常与吸烟者互动,我们认为呼吸治疗师在实施戒烟方面发挥领导作用尤为重要。