Vega Alonso T, Gil Costa M, Rodríguez Recio M J, de la Serna Higuera P
Dirección General de Salud Pública. Consejería de Sanidad y Bienestar Social. Valladolid. España.
Aten Primaria. 2003 Nov 30;32(9):517-23. doi: 10.1016/s0212-6567(03)70781-1.
To estimate the incidence of maculo-papular viral exanthemas and to describe the epidemiological and clinical patterns.
Observational descriptive study with a sample design.
154 practitioners from the Castilla y León Sentinel Network with a surveilled population of 23 237 people-year under 15 years old, notified in 2002 the cases of diseases by means of a standard form with the variables and inclusion and exclusion criteria.
It was included the maculo-papular exanthemas associated to a presumable systemic virus disease in patients under 15 years old. It was excluded the infectious mononucleose, the chickenpox, and other non viral infections or exanthemas.
368 cases were notified which represent a incidence rate of 158.37 cases per 10 000 (95% CI, 142.31-174.42). The incidence was maximum under four years old, more than 350 per 10 000, decreasing significantly in children over this age. Erythema infectiousum presented the highest rate, followed by exanthema subitum. The exanthemas caused by measles or rubella were insignificants.
Childhood exanthematous diseases of presumable viral etiology have an important incidence in primary care, although the majorities are banal and self-limited diseases. Clinical characteristics supported the suspicion diagnosis, which was consistent with the observed epidemiological description and expected presentations of each disease. Although serological analysis could diminish the uncertainly on notification and control of diseases submited to especial programs of vaccination and eradication, they would not improve substantially the diagnosis and treatment of these patients.
评估斑丘疹性病毒疹的发病率,并描述其流行病学和临床特征。
采用样本设计的观察性描述性研究。
来自卡斯蒂利亚-莱昂哨点网络的154名从业者,其监测人群为23237名15岁以下儿童人年。2002年,他们通过一份包含变量及纳入和排除标准的标准表格报告疾病病例。
纳入15岁以下患者中与疑似全身性病毒疾病相关的斑丘疹性皮疹。排除传染性单核细胞增多症、水痘以及其他非病毒感染或皮疹。
共报告368例病例,发病率为每10000人中有158.37例(95%可信区间,142.31 - 174.42)。发病率在4岁以下儿童中最高,超过每10000人350例,该年龄以上儿童发病率显著下降。传染性红斑发病率最高,其次是幼儿急疹。麻疹或风疹引起的皮疹发病率较低。
尽管大多数儿童期疑似病毒病因的出疹性疾病为轻症且自限性疾病,但在初级保健中仍有重要发病率。临床特征支持疑似诊断,这与观察到的流行病学描述以及每种疾病的预期表现一致。尽管血清学分析可减少提交给特殊疫苗接种和根除计划的疾病报告及控制中的不确定性,但对这些患者的诊断和治疗并无实质性改善。