Kim Hyung-Rae, Jung Ki-Young, Kim Soo-Yong, Ko Kyoung-Og, Lee Young-Mi, Kim Jae-Moon
VR Interface Research Team, Electronics and Telecommunications Research Institute, 161, Gajeong-dong, Yusong-gu, 305-350, Taejon, South Korea
Early Hum Dev. 2003 Dec;75(1-2):35-53. doi: 10.1016/j.earlhumdev.2003.09.004.
Animal studies indicate that postnatal adaptation and development of neonates could be different due to the birth method and that these effects may last throughout adulthood.
We applied a spatio-temporal analysis to EEG recordings of a group of neonates to investigate the influence of a cesarean section on maturation and extrauterine adaptation of the brain. EEG were recorded at 2 h and at 24 h after delivery.
A spectral analysis technique, the so-called Karhunen-Loeve (KL) method, was applied to EEG of 10 neonates from vaginal delivery and 17 from C-section to obtain the spatio-temporal eigenpatterns.
Spatio-temporal analysis showed noticeable pattern differences between the two groups. Compared to the C-section, the vaginal delivered neonate's EEG recordings showed a significant increase of amplitude at Fp1 in the pattern 24 h after the delivery, but not 2 h after delivery. Dynamics in this spectral analyses were not significantly different between both groups 2 h after delivery, but the regional differences increased during the next day between both groups.
This could come from the early insufficient complexity in C-section neonates. Global EEG complexity in C-section neonates fell short of that of vaginal delivered neonates 2 h after delivery. Many aspects of pattern change in C-section neonates followed the nature of vaginal delivered neonates. These could be considered as parts of a retarded transition of C-section neonates in the early adaptation, but some of the differences in global EEG pattern could not be explained in this way. Pattern analysis suggests that the neuronal activities of the neonatal brain are changing regionally concurrent with bi-hemispheric global dynamics. Moreover, the delivery modes could have an influence on the early postneonatal adaptation of the physiological activity in brain.
动物研究表明，由于分娩方式的不同，新生儿的产后适应和发育可能会有所差异，并且这些影响可能会持续到成年期。
我们对一组新生儿的脑电图记录进行了时空分析，以研究剖宫产对大脑成熟和宫外适应的影响。在分娩后2小时和24小时记录脑电图。
采用一种光谱分析技术，即所谓的卡尔胡宁-洛伊夫（KL）方法，对10例经阴道分娩的新生儿和17例剖宫产新生儿的脑电图进行分析，以获得时空特征模式。
时空分析显示两组之间存在明显的模式差异。与剖宫产组相比，经阴道分娩的新生儿在分娩后24小时的脑电图记录中，模式在Fp1处的振幅显著增加，但在分娩后2小时没有增加。两组在分娩后2小时的光谱分析动态没有显著差异，但在第二天两组之间的区域差异增加。
这可能源于剖宫产新生儿早期复杂性不足。剖宫产新生儿在分娩后2小时的全脑电图复杂性低于经阴道分娩的新生儿。剖宫产新生儿模式变化的许多方面遵循经阴道分娩新生儿的特征。这些可被视为剖宫产新生儿在早期适应中延迟过渡的一部分，但全脑电图模式的一些差异无法用这种方式解释。模式分析表明，新生儿大脑的神经元活动在区域上与双半球整体动态同时发生变化。此外，分娩方式可能会对新生儿出生后早期大脑生理活动的适应产生影响。
