分娩宫缩对新生大鼠儿茶酚胺释放及呼吸频率的影响。
Effects of labor contractions on catecholamine release and breathing frequency in newborn rats.
作者信息
Ronca April E, Abel Regina A, Ronan Patrick J, Renner Kenneth J, Alberts Jeffrey R
机构信息
Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
出版信息
Behav Neurosci. 2006 Dec;120(6):1308-14. doi: 10.1037/0735-7044.120.6.1308.
Abstract
Plasma catecholamines in newborn rats (0-2 hr old) were analyzed following vaginal birth, cesarean section with simulated labor contractions, or cesarean section without labor contractions. Upon delivery, pups were exposed to key elements of the rat's natural birth process, that is, umbilical cord occlusion, tactile stimulation, and cooling. Only pups exposed to actual or simulated labor showed an immediate rise in norepinephrine and epinephrine. Initial postpartum respiratory frequencies were higher in vaginal than in cesarean delivered pups and, in all groups, inversely correlated with catecholamine titers, suggesting respiratory distress or transient tachypnea at lower catecholamine levels. These findings establish a rat model for analyzing effects of labor on neonatal adaptive response during the transition from prenatal to postnatal life.
摘要
对经阴道分娩、模拟宫缩剖宫产或无宫缩剖宫产出生的新生大鼠（出生0 - 2小时）的血浆儿茶酚胺进行了分析。分娩时，幼崽经历了大鼠自然分娩过程的关键环节，即脐带闭塞、触觉刺激和降温。只有经历实际或模拟分娩的幼崽去甲肾上腺素和肾上腺素立即升高。经阴道分娩的幼崽产后初始呼吸频率高于剖宫产出生的幼崽，并且在所有组中，呼吸频率与儿茶酚胺水平呈负相关，这表明在儿茶酚胺水平较低时存在呼吸窘迫或短暂呼吸急促。这些发现建立了一个大鼠模型，用于分析分娩对从产前到产后生活过渡期间新生儿适应性反应的影响。
相似文献
1
Effects of labor contractions on catecholamine release and breathing frequency in newborn rats.分娩宫缩对新生大鼠儿茶酚胺释放及呼吸频率的影响。
Behav Neurosci. 2006 Dec;120(6):1308-14. doi: 10.1037/0735-7044.120.6.1308.
2
The effect of labor on maternal and fetal circulating catecholamines.分娩对母体和胎儿循环儿茶酚胺的影响。
Am J Obstet Gynecol. 1982 Sep 15;144(2):149-53. doi: 10.1016/0002-9378(82)90616-0.
3
Simulated uterine contractions facilitate fetal and newborn respiratory behavior in rats.模拟子宫收缩促进大鼠胎儿和新生儿的呼吸行为。
Physiol Behav. 1995 Nov;58(5):1035-41. doi: 10.1016/0031-9384(95)00155-c.
4
Influence of labor and neonatal hypoxia on sympathoadrenal activation and methionine enkephalin release in calves.
Am J Vet Res. 1993 Aug;54(8):1333-8.
5
[The influence of mode of delivery on the level of catecholamines in umbilical cord blood of neonates].[分娩方式对新生儿脐带血中儿茶酚胺水平的影响]
Zhonghua Yi Xue Za Zhi. 2009 May 19;89(19):1340-2.
6
Long-term reciprocal changes in dopamine levels in prefrontal cortex versus nucleus accumbens in rats born by Caesarean section compared to vaginal birth.与经阴道分娩的大鼠相比，剖宫产出生的大鼠前额叶皮质与伏隔核中多巴胺水平的长期相互变化。
Exp Neurol. 1997 May;145(1):118-29. doi: 10.1006/exnr.1997.6437.
7
Establishment of functional residual capacity in infants delivered vaginally and by elective cesarean section.经阴道分娩和择期剖宫产出生婴儿功能残气量的建立。
Early Hum Dev. 1991 Nov;27(1-2):103-10. doi: 10.1016/0378-3782(91)90031-w.
8
Fetal and maternal plasma catecholamine levels at elective cesarean section under general or epidural anesthesia versus vaginal delivery.全身麻醉或硬膜外麻醉下行择期剖宫产与阴道分娩时胎儿及母体血浆儿茶酚胺水平
Am J Obstet Gynecol. 1982 Apr 15;142(8):1004-10. doi: 10.1016/0002-9378(82)90783-9.
9
Neonatal adaptation: naloxone increases the catecholamine surge at birth.新生儿适应：纳洛酮会增加出生时儿茶酚胺的激增。
Pediatr Res. 1987 Jun;21(6):590-3. doi: 10.1203/00006450-198706000-00017.
10
The study of maternal and fetal plasma catecholamines levels during pregnancy and delivery.孕期及分娩期间母胎血浆儿茶酚胺水平的研究。
J Perinat Med. 1999;27(3):195-8. doi: 10.1515/JPM.1999.027.
引用本文的文献
1
Moderating effect of mode of delivery on the genetics of intelligence: Explorative genome-wide analyses in ALSPAC.分娩方式对智力遗传的调节作用：ALSPAC 中的全基因组探索性分析。
Brain Behav. 2018 Dec;8(12):e01144. doi: 10.1002/brb3.1144. Epub 2018 Oct 31.
2
Current Challenges in Neonatal Resuscitation: What is the Role of Adrenaline?新生儿复苏的当前挑战：肾上腺素的作用是什么？
Paediatr Drugs. 2018 Oct;20(5):417-428. doi: 10.1007/s40272-018-0300-6.
3
Maternal Heart Rate Variability during the First Stage of Labor.分娩第一产程中的产妇心率变异性
Front Physiol. 2017 Oct 9;8:774. doi: 10.3389/fphys.2017.00774. eCollection 2017.
4
The Elevated Rate of Cesarean Section and Its Contribution to Non-Communicable Chronic Diseases in Latin America: The Growing Involvement of the Microbiota.拉丁美洲剖宫产率上升及其对非传染性慢性病的影响：微生物群的作用日益凸显
Front Pediatr. 2017 Sep 4;5:192. doi: 10.3389/fped.2017.00192. eCollection 2017.
5
NEONATAL HYPOGLYCAEMIA AT CAPE COAST TEACHING HOSPITAL.海岸角教学医院的新生儿低血糖症
J West Afr Coll Surg. 2015 Apr-Jun;5(2):100-116.
6
The Effects of Inhaled β-Adrenergic Agonists in Transient Tachypnea of the Newborn.吸入性β-肾上腺素能激动剂对新生儿暂时性呼吸急促的影响。
Glob Pediatr Health. 2016 May 17;3:2333794X16645258. doi: 10.1177/2333794X16645258. eCollection 2016.
7
Planned Cesarean Delivery at Term and Adverse Outcomes in Childhood Health.足月计划性剖宫产与儿童期健康不良结局
JAMA. 2015 Dec 1;314(21):2271-9. doi: 10.1001/jama.2015.16176.
8
Low neonatal blood glucose levels in cesarean-delivered term newborns at Khartoum Hospital, Sudan.苏丹喀土穆医院剖宫产足月新生儿低血糖水平。
Diagn Pathol. 2014 Jun 9;9:112. doi: 10.1186/1746-1596-9-112.
9
Prematurely delivered rats show improved motor coordination during sensory-evoked motor responses compared to age-matched controls.与年龄匹配的对照组相比，早产大鼠在感觉诱发运动反应期间表现出更好的运动协调性。
Physiol Behav. 2014 May 10;130:75-84. doi: 10.1016/j.physbeh.2014.03.024. Epub 2014 Mar 28.
10
The effects of inhaled albuterol in transient tachypnea of the newborn.吸入沙丁胺醇对新生儿暂时性呼吸急促的影响。
Allergy Asthma Immunol Res. 2014 Mar;6(2):126-30. doi: 10.4168/aair.2014.6.2.126. Epub 2013 Nov 15.
本文引用的文献
1
Physiology of fetal lung fluid clearance and the effect of labor.胎儿肺液清除的生理学及分娩的影响。
Semin Perinatol. 2006 Feb;30(1):34-43. doi: 10.1053/j.semperi.2006.01.006.
2
Influence of temperature on metabolism and breathing during mammalian ontogenesis.温度对哺乳动物个体发育过程中新陈代谢和呼吸的影响。
Respir Physiol Neurobiol. 2005 Nov 15;149(1-3):155-64. doi: 10.1016/j.resp.2005.01.012.
3
Implications of hypoxic hypometabolism during mammalian ontogenesis.哺乳动物个体发育过程中低氧低代谢的影响。
Respir Physiol Neurobiol. 2004 Aug 12;141(3):345-56. doi: 10.1016/j.resp.2004.01.011.
4
Neonatal respiratory morbidity risk and mode of delivery at term: influence of timing of elective caesarean delivery.足月新生儿呼吸疾病发病风险与分娩方式：择期剖宫产时机的影响
Acta Paediatr. 2004 May;93(5):643-7. doi: 10.1111/j.1651-2227.2004.tb02990.x.
5
Delivery modes and neonatal EEG: spatial pattern analysis.分娩方式与新生儿脑电图：空间模式分析
Early Hum Dev. 2003 Dec;75(1-2):35-53. doi: 10.1016/j.earlhumdev.2003.09.004.
6
Hypothermia-induced respiratory arrest and recovery in neonatal rats.新生大鼠低温诱导的呼吸骤停与恢复
Respir Physiol Neurobiol. 2003 Aug 14;137(1):29-40. doi: 10.1016/s1569-9048(03)00112-5.
7
Beneficial impact of term labor: nonenzymatic antioxidant reserve in the human fetus.足月分娩的有益影响：人类胎儿的非酶抗氧化储备
Am J Obstet Gynecol. 2003 Jul;189(1):181-8. doi: 10.1067/mob.2003.357.
8
Differential vulnerability of male versus female rats to long-term effects of birth insult on brain catecholamine levels.雄性与雌性大鼠对出生时的损伤对脑儿茶酚胺水平长期影响的差异易感性。
Exp Neurol. 2003 Jul;182(1):208-19. doi: 10.1016/s0014-4886(03)00079-7.
9
Invited review: Clearance of lung liquid during the perinatal period.
J Appl Physiol (1985). 2002 Oct;93(4):1542-8. doi: 10.1152/japplphysiol.00092.2002.
10
The effect of labor on olfactory exposure learning within the first postnatal hour.
Behav Neurosci. 2002 Apr;116(2):206-11. doi: 10.1037//0735-7044.116.2.206.
Zotero 插件