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系谱数据与人类长寿的生物人口学

Genealogical data and the biodemography of human longevity.

作者信息

Gavrilov Leonid A, Gavrilova Natalia S, Olshansky S Jay, Carnes Bruce A

机构信息

Center on Aging, NORC/University of Chicago, USA.

出版信息

Soc Biol. 2002 Fall-Winter;49(3-4):160-73. doi: 10.1080/19485565.2002.9989056.

Abstract

Biodemography of human longevity is an emerging interdisciplinary field of sociobiological research with deep historical roots. Two research questions are examined in this article: (1) What evidence is there for the familial transmission of human longevity?, and (2) what are the effects of parental age at reproduction on offspring longevity, and in particular, are there long-term adverse health consequences associated with the trend toward delayed reproduction? The ability of scientists to conduct biodemographic studies depends not only on merging theoretical and methodological elements from the biological and demographic/actuarial sciences, but unique sources of data and statistical methods must also be developed. In this article we describe how gencalogical data have been used for over a century to explore basic questions about human longevity, and how similar kinds of data now being developed are driving the formation of new testable research hypotheses in the field of biodemography.

摘要

人类长寿生物人口学是一个新兴的社会生物学研究跨学科领域,有着深厚的历史根源。本文探讨了两个研究问题:(1)人类长寿的家族遗传有哪些证据?(2)父母生育年龄对后代寿命有何影响,特别是,延迟生育趋势是否会带来长期的不良健康后果?科学家进行生物人口学研究的能力不仅取决于融合生物学和人口统计学/精算科学的理论和方法要素,还必须开发独特的数据来源和统计方法。在本文中,我们描述了一个多世纪以来系谱数据是如何被用于探索关于人类长寿的基本问题,以及目前正在开发的类似数据如何推动生物人口学领域新的可检验研究假设的形成。

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