Lacroix P, Linée P, Le Pollés J B
C R Seances Soc Biol Fil. 1977;171(5):1075-80.
Influence of ethaverine was compared to papaverine on the development of dysrhythmias observed in the unanesthetized dog following coronary ligation. Papaverine generally induced the reappearance of ectopic beats. In most cases, ethaverine induced the normalization of the electrocardiogram. This favourable effect of ethaverine distinguished it from papaverine; however it was moderate, transient and weaker than that of classical antidysrhythmic drugs. According to these results and those of previous experimental data, ethaverine seems to be devoid of "malignant properties".
将罂粟碱与乙基罂粟碱对冠状动脉结扎后未麻醉犬所观察到的心律失常发展的影响进行了比较。罂粟碱通常会诱发异位搏动再次出现。在大多数情况下，乙基罂粟碱可使心电图恢复正常。乙基罂粟碱的这种有利作用使其有别于罂粟碱；然而，这种作用是适度的、短暂的，且比经典抗心律失常药物的作用弱。根据这些结果以及先前实验数据的结果，乙基罂粟碱似乎没有“恶性特性”。
