Van Den Driessche J, Linée P, Lacroix P, Le Pollès J B
C R Seances Soc Biol Fil. 1977;171(5):1081-7.
Using venous infusion (0.25 mg/kg min.), l-eburnamonine decreases the electroencephalographic modifications induced by acute asphyxic anoxia in curarized rats. This activity appears when the total dose administrated before the first asphyxia is approximatively 5 mg/kg. In such conditions, its protective activity is precocious and long lasting. In the same experimental conditions, vincamine assumes a protective activity only during a short time. The results are discussed in terms of selectivity of the method used and in terms of cerebral antihypoxic properties of l-eburnamonine.
使用静脉输注（0.25毫克/千克·分钟），利血胺可减轻箭毒化大鼠急性窒息性缺氧引起的脑电图改变。当首次窒息前给予的总剂量约为5毫克/千克时，这种活性就会出现。在这种情况下，其保护活性出现早且持续时间长。在相同的实验条件下，长春胺仅在短时间内具有保护活性。根据所用方法的选择性以及利血胺的脑抗缺氧特性对结果进行了讨论。
