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In dogs, the urinary clearance of IPNA-3H is very near GFR (ratio CIPNA-3H/GFR = 0,92). This ratio is not modified by cocaine. In our experimental conditions, we observe no tubulary secretion of IPNA-3H.
在犬类中,IPNA - 3H的尿清除率非常接近肾小球滤过率(CIPNA - 3H/GFR比值 = 0.92)。该比值不受可卡因影响。在我们的实验条件下,我们未观察到IPNA - 3H的肾小管分泌。