抗缪勒管激素信号传导：从受体到靶基因
AMH signaling: from receptor to target gene.
作者信息
Visser Jenny A
机构信息
Department of Internal Medicine, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands.
出版信息
Mol Cell Endocrinol. 2003 Dec 15;211(1-2):65-73. doi: 10.1016/j.mce.2003.09.012.
Anti-Müllerian hormone (AMH), also known as Müllerian inhibiting substance (MIS), is a member of the transforming growth factor beta (TGFbeta) superfamily and plays a crucial role during male sexual differentiation. Although the AMH type II receptor has been identified, the identity of the other signaling components has remained unknown. This review describes the identification of candidate AMH type I receptors and an AMH-target gene involved in Müllerian duct regression.
抗苗勒管激素（AMH），也称为苗勒管抑制物质（MIS），是转化生长因子β（TGFβ）超家族的成员，在男性性分化过程中起关键作用。尽管II型AMH受体已被鉴定，但其他信号成分的身份仍然未知。这篇综述描述了参与苗勒管退化的I型AMH受体候选物和一个AMH靶基因的鉴定。
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