Matloub H S, Jensen P, Grunert B K, Sanger J R, Yousif N J
Department of Plastic and Reconstructive Surgery, Medical College of Wisconsin, Milwaukee.
Ann Plast Surg. 1992 Dec;29(6):508-11. doi: 10.1097/00000637-199212000-00005.
This study evaluated two types of prosthetic mesh and autogenous fascia in long-term abdominal wall reconstruction for rats. Marlex mesh, Gore-Tex patch, and autogenous fascia were implanted and left in place for 1 year. Materials were removed and evaluated using tensile strength of the material, tensile strength of the suture line, and adhesions. No change in the tensile strength of any of the materials were found at 1 year follow-up. Tensile strengths were significantly greater for Gore-Tex patch and Marlex mesh than the autogenous fascia. The Marlex mesh, however, had a weak and a strong tensile strength direction. These were significantly different (p < 0.05). Suture line tensile strength was greater for autogenous fascia and Marlex mesh than it was for the Gore-Tex patch, which was significantly weaker (p < 0.05). The greatest number of adhesions were seen in the Marlex mesh group. No significant difference was present in adhesions between Gore-Tex patch and autogenous fascia. In summary, autogenous fascia showed virtually no adhesions and good suture line strength. While it was the weakest of the three materials examined, the strength was still within the normal range and adequate for abdominal wall reconstruction.
本研究评估了两种人工合成补片和自体筋膜用于大鼠长期腹壁重建的效果。植入Marlex补片、Gore-Tex补片和自体筋膜并留置1年。取出材料后,通过材料的拉伸强度、缝线的拉伸强度和粘连情况进行评估。在1年随访时,未发现任何材料的拉伸强度有变化。Gore-Tex补片和Marlex补片的拉伸强度显著高于自体筋膜。然而,Marlex补片有一个弱拉伸强度方向和一个强拉伸强度方向,二者差异显著(p<0.05)。自体筋膜和Marlex补片的缝线拉伸强度高于Gore-Tex补片,Gore-Tex补片的缝线拉伸强度显著较弱(p<0.05)。Marlex补片组的粘连数量最多。Gore-Tex补片和自体筋膜之间的粘连无显著差异。总之,自体筋膜几乎没有粘连且缝线强度良好。虽然它是所检测的三种材料中最弱的,但强度仍在正常范围内,足以用于腹壁重建。