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Small bowel transit and gastric emptying after biliodigestive anastomosis using the uncut jejunal loop.

作者信息

Klaus Alexander, Hinder Ronald A, Nguyen Justin H H, Nelson Kevin L

机构信息

Department of Surgery, Mayo Clinic Jacksonville, Jacksonville, FL 32224, USA.

出版信息

Am J Surg. 2003 Dec;186(6):747-51. doi: 10.1016/j.amjsurg.2003.08.025.

Abstract

BACKGROUND

The Roux-en-Y loop is an effective procedure for biliodigestive drainage. However, up to 15% of patients suffer from postoperative cholangitis or blind loop syndrome. A new technique to prevent motility abnormalities has been developed.

METHODS

Male Lewis rats were used to compare gastric emptying and transit in the small bowel after either a standard Roux-en-Y anastomosis or a new biliodigestive anastomosis technique which involves creating an "uncut" jejunal loop with luminal occlusion. Unoperated rats served as controls. (99)Technetium HIDA and (111)Indium-tagged amberlite were respectively used to investigate small bowel transit and gastric emptying.

RESULTS

Histopathology showed distinctive abnormalities only in the liver of conventional Roux-en-Y animals. No recanalization of the obliterated gut lumen occurred in uncut Roux animals. Distribution of (99)Tc-HIDA and (111)In showed were similar in both groups. Gastric emptying is slowed in both groups.

CONCLUSIONS

The uncut proximal jejunum loop is a good alternative to the conventional Roux-en-Y loop and showed preserved small bowel motility and adequate jejunal transit. Gastric emptying is slowed in both groups.

摘要

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