Perino L E, Adcock K A, Goff J S
Division of Gastroenterology, University of Colorado Health Sciences Center, Denver.
Am J Gastroenterol. 1988 Apr;83(4):380-5.
Roux-en-Y patients have symptoms that vary from almost none to inability to tolerate oral feedings. This study was designed to determine whether there is a relationship between a patient's symptoms and the function of the gastric remnant or the Roux-limb. Gastric remnant and Roux-limb emptying were studied in eight patients with technetium-99m-labeled oatmeal and Roux-limb motor activity was measured with a water-perfused manometry system. We found that gastric emptying was rarely significantly slowed, but emptying of the Roux-limb was delayed in several patients. We also found that there was a rough correlation between the patient's symptoms and the degree of abnormal motility found in the Roux-limb. There is no known reason for these abnormalities in Roux-limb function in some patients after a Roux-en-Y, but our finding of worse abnormalities in those who had multiple previous gastric surgeries suggests that the symptoms and dysfunction may be related to the number of surgeries, as well as to the type of surgery.
Roux-en-Y手术患者的症状差异很大,从几乎没有症状到无法耐受经口进食。本研究旨在确定患者症状与胃残端或Roux袢功能之间是否存在关联。使用锝-99m标记的燕麦片对8例患者的胃残端和Roux袢排空情况进行了研究,并用水灌注测压系统测量了Roux袢的运动活性。我们发现胃排空很少明显减慢,但部分患者的Roux袢排空延迟。我们还发现患者症状与Roux袢中发现的异常运动程度之间存在大致的相关性。目前尚不清楚Roux-en-Y手术后部分患者Roux袢功能出现这些异常的原因,但我们发现既往接受过多次胃部手术的患者异常情况更严重,这表明症状和功能障碍可能与手术次数以及手术类型有关。