Wepler R, Burkhardt H, Burkhardt F, Rommel K
J Clin Chem Clin Biochem. 1977 Dec;15(12):653-5. doi: 10.1515/cclm.1977.15.1-12.653.
Parameters of collagen metabolism were investigated in guinea pigs, both untreated and treated with glucocorticoids. One series consisted of animals housed under normal conditions, the others of SPF animals from the same strain. There are marked differences in certain parameters, including the hydroxyproline content and the reaction of the collagen to glucocorticoids.
在豚鼠中研究了胶原蛋白代谢参数,这些豚鼠有的未接受治疗,有的接受了糖皮质激素治疗。一组由饲养在正常条件下的动物组成,另一组由来自同一品系的无特定病原体动物组成。在某些参数上存在显著差异,包括羟脯氨酸含量以及胶原蛋白对糖皮质激素的反应。