Chan Henry H L, Kono Taro
The Division of Dermatology, Department of Medicine, University of Hong Kong, Room 802 Administration Building, Queen Mary Hospital, Hong Kong, PR China.
Skinmed. 2003 Mar-Apr;2(2):89-96; quiz 97-8. doi: 10.1111/j.1540-9740.2003.01706.x.
Nevus of Ota, or nevus fuscoceruleus ophthalmomaxillaris, is a dermal melanocytic hamartoma that presents as bluish hyperpigmentation along the first or second branches of the trigeminal nerve. Extra-cutaneous involvement has been reported, especially ocular involvement. Nevus of Ota affects between 0.014%-0.034% of the Asian population. Clinical differential diagnoses include facial cafe-au-lait patch, spilus nevus, and acquired bilateral nevus of Ota-like macules. Previous treatment modalities, including cryotherapy and microsurgery, can be associated with scarring. In the last decade, the use of Q-switched lasers has revolutionized the treatment of this condition. This review summarizes the clinical, histologic, and management aspects of this dermal melanocytic hamartoma.
太田痣,又称眼上颌蓝褐色痣,是一种真皮黑素细胞错构瘤,表现为沿三叉神经第一或第二分支分布的蓝色色素沉着。已有皮肤外受累的报道,尤其是眼部受累。太田痣在亚洲人群中的发病率为0.014%-0.034%。临床鉴别诊断包括面部咖啡牛奶斑、斑痣和获得性双侧太田痣样斑。以往的治疗方法,包括冷冻疗法和显微外科手术,可能会导致瘢痕形成。在过去十年中,调Q激光的应用彻底改变了这种疾病的治疗方法。本文综述了这种真皮黑素细胞错构瘤的临床、组织学和治疗方面。