Severin S E
Biokhimiia. 1992 Sep;57(9):1285-95.
The history of discovery of carnosine and anserine is reviewed with special reference to the structure and distribution of the dipeptides in various tissues during ontogenesis. The state of the dipeptides in muscle cells, their metabolism and role in muscle activity are considered. The properties of carnosine and anserine phosphoric esters are described, and their putative role in mitochondrial oxidative phosphorylation is discussed. The membranotropic activity of carnosine and anserine is demonstrated.
本文回顾了肌肽和鹅肌肽的发现历史,并特别提及了这些二肽在个体发育过程中于各种组织中的结构和分布。文中还探讨了二肽在肌肉细胞中的状态、它们的代谢以及在肌肉活动中的作用。描述了肌肽和鹅肌肽磷酸酯的特性,并讨论了它们在线粒体氧化磷酸化中可能发挥的作用。此外,还展示了肌肽和鹅肌肽的膜亲和活性。