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血浆催乳素作为未服药精神分裂症门诊患者复发的预测指标。

Plasma prolactin as a predictor of relapse in drug-free schizophrenic outpatients.

作者信息

Kirkpatrick B, Carpenter W T, Maeda K, Buchanan R W, Breier A, Tamminga C A

机构信息

University of Maryland School of Medicine, Baltimore.

出版信息

Biol Psychiatry. 1992 Dec 1;32(11):1049-54. doi: 10.1016/0006-3223(92)90067-a.

DOI:10.1016/0006-3223(92)90067-a
PMID:1467385
Abstract

A low plasma prolactin concentration has been reported to be associated with an increased risk of subsequent relapse in patients with schizophrenia. Prolactin concentration was measured in samples from stable schizophrenic men who were outpatients just prior to neuroleptic withdrawal. No relationship between prolactin concentration and time to subsequent relapse was found. Prolactin concentration may predict time to relapse only in populations characterized by specific demographic features or medication history.

摘要

据报道,低血浆催乳素浓度与精神分裂症患者后续复发风险增加有关。对处于稳定状态、在停用抗精神病药物之前为门诊患者的男性精神分裂症患者的样本进行了催乳素浓度测量。未发现催乳素浓度与后续复发时间之间存在关联。催乳素浓度可能仅在具有特定人口统计学特征或用药史的人群中能够预测复发时间。

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Plasma prolactin as a predictor of relapse in drug-free schizophrenic outpatients.血浆催乳素作为未服药精神分裂症门诊患者复发的预测指标。
Biol Psychiatry. 1992 Dec 1;32(11):1049-54. doi: 10.1016/0006-3223(92)90067-a.
2
Effect of neuroleptic withdrawal on plasma prolactin: a possible marker of receptor adaptation.抗精神病药物撤药对血浆催乳素的影响:受体适应性的一个可能标志物。
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Pupillary constriction during haloperidol treatment as a predictor of relapse following drug withdrawal in schizophrenic patients.氟哌啶醇治疗期间瞳孔收缩作为精神分裂症患者停药后复发的预测指标。
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Neuroleptic responsivity of negative and positive symptoms in schizophrenia.精神分裂症阴性和阳性症状的抗精神病药物反应性
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Phenothiazine-induced decompensation.
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Clinical predictors of relapse following neuroleptic withdrawal.抗精神病药物撤药后复发的临床预测因素。
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Plasma prolactin and homovanillic acid as markers for psychopathology and abnormal movements during maintenance haloperidol treatment in male patients with schizophrenia.血浆催乳素和高香草酸作为男性精神分裂症患者维持性氟哌啶醇治疗期间精神病理学和异常运动的标志物。
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引用本文的文献

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Abnormally low prolactin levels in schizophrenia patients after switching to aripiprazole in a randomized trial: a biomarker for rebound in psychotic symptoms?在一项随机试验中,精神分裂症患者换用阿立哌唑后催乳素水平异常降低:精神病症状反弹的生物标志物?
BMC Psychiatry. 2020 Nov 23;20(1):552. doi: 10.1186/s12888-020-02957-7.
2
Baseline serum prolactin in drug-naive, first-episode schizophrenia and outcome at five years: is it a predictive factor?初发未用药的精神分裂症患者的基线血清催乳素水平与五年预后:它是一个预测因素吗?
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