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血浆催乳素作为未服药精神分裂症门诊患者复发的预测指标。

Plasma prolactin as a predictor of relapse in drug-free schizophrenic outpatients.

作者信息

Kirkpatrick B, Carpenter W T, Maeda K, Buchanan R W, Breier A, Tamminga C A

机构信息

University of Maryland School of Medicine, Baltimore.

出版信息

Biol Psychiatry. 1992 Dec 1;32(11):1049-54. doi: 10.1016/0006-3223(92)90067-a.

Abstract

A low plasma prolactin concentration has been reported to be associated with an increased risk of subsequent relapse in patients with schizophrenia. Prolactin concentration was measured in samples from stable schizophrenic men who were outpatients just prior to neuroleptic withdrawal. No relationship between prolactin concentration and time to subsequent relapse was found. Prolactin concentration may predict time to relapse only in populations characterized by specific demographic features or medication history.

摘要

据报道,低血浆催乳素浓度与精神分裂症患者后续复发风险增加有关。对处于稳定状态、在停用抗精神病药物之前为门诊患者的男性精神分裂症患者的样本进行了催乳素浓度测量。未发现催乳素浓度与后续复发时间之间存在关联。催乳素浓度可能仅在具有特定人口统计学特征或用药史的人群中能够预测复发时间。

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