Jehan A H, Chowdhury S B, Sultana F, Haque J A, Khatun S, Karim M A
Deptt. of Obst. & Gynae., Bangabandhu Sheikh Mujib Medical University, Dhaka.
Bangladesh Med Res Counc Bull. 2003 Aug;29(2):67-77.
Infants born for small for date (SFD) fetuses have an increased risk of perinatal mortality and morbidity. Different methods have been applied to identify these fetuses including history, clinical examination and ultrasonography. Ultrasonography has a better predictive value and majority of such fetuses can be identified. Measurements of the fetal biparietal diameter (BPD), abdominal circumference (AC) and femur length (FL) charts are widely used in dating pregnancies and follow-up of pregnant women in assessing fetal growth, identification of small for date (SFD) and growth retarded fetuses. This prospective study was performed to construct fetal chart for BPD, AC and FL at different gestational weeks from the Bangladeshi pregnant women. Seven hundred and ten women had ultrasonic measurements of fetal BPD, AC and FL between 12 to 42 weeks of pregnancy. Centiles, mean and the standard deviation (SD) were calculated for BPD, AC and FL. Mean maternal age was 24.73 +/- 4.48 (Mean +/- SD) and 310 (43.7%) were primigravidae. There was a gradual increase of the BPD (outer-inner), AC and FL measurements of 5th, 10th, 50th and 90th Centiles upto 38th weeks of gestation with a gradual increase of SD showing increasing dispersion of data. In cases of BPD and AC, After 38th weeks of gestation the Centiles showed a slower growth rate towards 42 weeks of pregnancy. This slower growth rate from 38 weeks of pregnancy was not noted in case of femur length. Fetal charts with the raw data for each measurement with superimposed fitted lines derived from polynomial (quadratic) regression were constructed. Quadratic model showed good fit to the data during construction of fetal charts. The new fetal measurement charts of BPD, AC and FL are unique for the Bangladeshi population and have not been found similar in the later weeks of pregnancy to those published for other Caucasian populations. These charts will help the clinicians and sonographers in dating pregnancy, identifying SFD and growth retarded fetuses.
小于胎龄儿(SFD)出生的婴儿围产期死亡率和发病率增加。已应用不同方法来识别这些胎儿,包括病史、临床检查和超声检查。超声检查具有更好的预测价值,大多数此类胎儿可以被识别。胎儿双顶径(BPD)、腹围(AC)和股骨长度(FL)图表测量广泛用于确定孕周以及在评估胎儿生长、识别小于胎龄儿(SFD)和生长受限胎儿时对孕妇进行随访。本前瞻性研究旨在构建孟加拉国孕妇在不同孕周时BPD、AC和FL的胎儿图表。710名妇女在怀孕12至42周期间接受了胎儿BPD、AC和FL的超声测量。计算了BPD、AC和FL的百分位数、平均值和标准差(SD)。孕妇平均年龄为24.73±4.48(平均值±标准差),初产妇有310名(43.7%)。直至妊娠38周,第5、10、50和90百分位数的BPD(外-内)、AC和FL测量值逐渐增加,SD也逐渐增加,表明数据离散度增加。在BPD和AC的情况下,妊娠38周后,百分位数在接近妊娠42周时生长速度较慢。股骨长度在妊娠38周后未出现这种生长速度减慢的情况。构建了包含每次测量原始数据以及由多项式(二次)回归得出的叠加拟合线的胎儿图表。二次模型在构建胎儿图表期间对数据显示出良好的拟合。BPD、AC和FL的新胎儿测量图表对于孟加拉国人群来说是独特的,在妊娠后期未发现与为其他白种人群发布的图表相似。这些图表将有助于临床医生和超声检查人员确定孕周、识别小于胎龄儿和生长受限胎儿。