Leung T N, Pang M W, Daljit S S, Leung T Y, Poon C F, Wong S M, Lau T K
Fetal Medicine Unit, Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, The Prince of Wales Hospital, Hong Kong.
Ultrasound Obstet Gynecol. 2008 Mar;31(3):321-7. doi: 10.1002/uog.5192.
To construct new reference charts and equations for fetal biometry in the Hong Kong ethnic Chinese population, and to compare them with existing references from different populations.
This was a prospective observational study involving 709 women with singleton pregnancies and confirmed gestational age. For the purposes of this study, each woman was scanned once only, between 12 and 40 completed weeks of gestation, and the following fetal biometric measurements were recorded: biparietal diameter, head circumference, abdominal circumference and femur length. For each measurement, regression models were fitted to estimate the mean and SD at each gestational age. For comparison, the fetal biometric measurements of other populations at each gestation were expressed as Z-scores calculated with our reference equations. Results were presented graphically across the different gestational ages to allow visual comparison.
New charts and reference equations are reported in this Hong Kong Chinese population for fetal outer-inner and outer-outer biparietal diameter, head circumference, abdominal circumference and femur length. Equations for dating of pregnancy are presented. Our charts were very similar to those of the Singaporean population for most parameters. The main difference in our fetal biometric measurements compared with those of the UK and French populations was in FL.
Our new set of reference centiles for fetal biometric measurements and equations for dating of pregnancy in a Hong Kong Chinese population are ready for clinical use and research in appropriate ethnic Chinese groups.
构建香港华裔人群胎儿生物测量的新参考图表和方程,并将其与不同人群的现有参考标准进行比较。
这是一项前瞻性观察性研究,纳入了709名单胎妊娠且孕周确定的女性。在本研究中,每位女性在妊娠12至40足周期间仅接受一次扫描,并记录以下胎儿生物测量数据:双顶径、头围、腹围和股骨长度。对于每项测量,拟合回归模型以估计每个孕周的均值和标准差。为了进行比较,将其他人群在每个孕周的胎儿生物测量数据表示为使用我们的参考方程计算得出的Z分数。结果以图形方式呈现于不同孕周,以便进行直观比较。
报告了香港华裔人群胎儿内外侧和外外侧双顶径、头围、腹围和股骨长度的新图表和参考方程。给出了妊娠预产期方程。我们的图表在大多数参数上与新加坡人群的图表非常相似。与英国和法国人群相比,我们胎儿生物测量的主要差异在于股骨长度。
我们为香港华裔人群胎儿生物测量新制定的一组参考百分位数和妊娠预产期方程可供合适的华裔人群用于临床和研究。