Department of Maternal-Fetal Medicine, High-Risk Unit, Los Farallones Clinic, Cali, Colombia.
J Ultrasound Med. 2013 Jul;32(7):1215-25. doi: 10.7863/ultra.32.7.1215.
To create reference charts for fetal sonographic biometric measurements in a population of pregnant women living in the third largest city in Colombia and compare them with charts included in ultrasound machines.
The data were obtained from women with a single pregnancy and confirmed gestational (menstrual) age between 12 and 40 weeks. All women were recruited specifically for the study, and every fetus was measured only once for biparietal diameter, head circumference, abdominal circumference, and femur length. Raw data for each fetal measurement were modeled by fitting regression models separately to estimate the mean and standard deviation as a function of gestational age. Percentile curves were constructed for each measurement by gestational age using these two regression models. We compared our mean z scores with those expected by reference equations.
Measurements were obtained for 792 fetuses. A cubic polynomial model was the best-fitted regression model to describe the relationships between each fetal measurement and gestational age. The standard deviation for each measurement was estimated by simple linear regression as a function of gestational age. Comparison of our mean z scores with those by reference equations showed significant differences in some fetal measurements (P < .01).
We present a set of reference percentile charts, tables, and formulas for fetal biometric measurements from a Colombian population. We believe that our fetal charts could be used nationwide in Colombia; nevertheless, a national sample will contribute to their validation and promotion of the development of Colombian fetal size charts.
制作哥伦比亚第三大城市孕妇人群胎儿超声生物测量的参考图表,并与超声机中包含的图表进行比较。
该数据来自于单胎妊娠且经确认的 12 至 40 孕周的孕妇。所有女性都是专门为该研究招募的,每个胎儿的双顶径、头围、腹围和股骨长度仅测量一次。通过分别拟合回归模型来对每个胎儿测量的原始数据进行建模,以估计均值和标准差作为胎龄的函数。使用这两个回归模型,通过胎龄构建每个测量的百分位数曲线。我们将我们的平均 z 分数与参考方程预期的进行了比较。
共获得了 792 个胎儿的测量值。三次多项式模型是描述每个胎儿测量值与胎龄之间关系的最佳拟合回归模型。每个测量的标准差通过简单线性回归作为胎龄的函数进行估计。我们的平均 z 分数与参考方程的比较显示,在一些胎儿测量值上存在显著差异(P <.01)。
我们提出了一组哥伦比亚人群胎儿生物测量的参考百分位数图表、表格和公式。我们认为,我们的胎儿图表可以在哥伦比亚全国范围内使用;然而,全国性的样本将有助于其验证和促进哥伦比亚胎儿大小图表的发展。