Kirby Michael, Kennedy Craig H
Vanderbilt University, Nashville, Tennessee, USA.
J Exp Anal Behav. 2003 Sep;80(2):253-60. doi: 10.1901/jeab.2003.80-253.
The effects of rapid-eye movement sleep deprivation (REMSD) in rats were studied in relation to variable-interval (VI) reinforcement schedule value. Initially, lever pressing was maintained on a VI 30-s schedule of food pellet delivery. After a baseline was established, rats were repeatedly exposed to 96 hr of REMSD and control conditions of an equivalent duration. Responding decreased following REMSD but not after exposure to control conditions. Lever pressing was then maintained on a VI 15-s schedule of food pellet delivery and exposure to the REMSD and control conditions was repeated. Under this condition following repeated REMSD exposures, rates of lever pressing became similar to baseline responding. A VI 30-s schedule of food pellet delivery was then reinstated and REMSD and control conditions were repeated. Lever pressing following exposure to the REMSD condition decreased for 3 of 4 rats. Results suggest that VI schedule value influences the effects of REMSD on responding.
研究了大鼠快速眼动睡眠剥夺(REMSD)与可变间隔(VI)强化程序值的关系。最初,在每30秒给予一次食物颗粒的可变间隔程序下维持杠杆按压行为。在建立基线后,大鼠反复经历96小时的快速眼动睡眠剥夺及同等时长的对照条件。快速眼动睡眠剥夺后反应减少,但暴露于对照条件后未出现这种情况。然后在每15秒给予一次食物颗粒的可变间隔程序下维持杠杆按压行为,并重复快速眼动睡眠剥夺和对照条件的暴露。在这种条件下,经过多次快速眼动睡眠剥夺暴露后,杠杆按压速率变得与基线反应相似。随后恢复每30秒给予一次食物颗粒的可变间隔程序,并重复快速眼动睡眠剥夺和对照条件。在4只大鼠中,有3只在暴露于快速眼动睡眠剥夺条件后杠杆按压行为减少。结果表明,可变间隔程序值会影响快速眼动睡眠剥夺对反应的影响。