Vega M L, Vega J, Vega J M, Moneo I, Sánchez E, Miranda A
Centro de Salud Portillo, Valladolid, Spain.
Pediatr Allergy Immunol. 2003 Dec;14(6):482-6. doi: 10.1046/j.0905-6157.2003.00066.x.
Cutaneous lesions caused by pine processionary caterpillar (Thaumetopoea pityocampa, TP) are frequent in pinewood areas. However, no epidemiological studies have been performed so far in the pediatric population. In this study, we evaluated the relevance of reactions to pine processionary caterpillar in the pediatric population of our environment and determined the possible role of an IgE-mediated mechanism. A questionnaire was developed and given to 1,101 children and adolescents ranging from 3 to 17 years of age from rural areas with large pine forests. A total of 653 questionnaires were answered by the children or their parents. The search for immunoglobulin E (IgE)-mediated cases was based on the presence of a suspected reaction to caterpillar and confirmed by in vivo (skin prick) and in vitro (immunoblotting) tests. Sixty of the 653 people interviewed (9.18%) identified a cutaneous reaction from exposure to the processionary caterpillar. Within this group only four cases (6.7%) were because of an IgE-mediated mechanism. The predominant clinical feature of these patients with allergy to caterpillar was contact urticaria. We present the first study of cutaneous reactions to pine processionary caterpillar in a large pediatric population. This is a frequent pathology in pinery zones and only in a minority of the cases are because of an IgE-mediated allergic mechanism. This fact contrasts with studies in adults, where this percentage is much greater.
由松异舟蛾（Thaumetopoea pityocampa，TP）引起的皮肤病变在松林地区很常见。然而，迄今为止尚未在儿科人群中进行过流行病学研究。在本研究中，我们评估了我们所在环境中儿科人群对松异舟蛾反应的相关性，并确定了IgE介导机制的可能作用。我们设计了一份问卷，并发放给来自有大片松林的农村地区、年龄在3至17岁的1101名儿童和青少年。共有653名儿童或其父母回答了问卷。对免疫球蛋白E（IgE）介导病例的筛查基于对毛虫疑似反应的存在，并通过体内（皮肤点刺）和体外（免疫印迹）试验进行确认。在接受采访的653人中，有60人（9.18%）确认有因接触松异舟蛾而出现的皮肤反应。在这一组中，只有4例（6.7%）是由IgE介导的机制引起的。这些对毛虫过敏的患者的主要临床特征是接触性荨麻疹。我们首次对大量儿科人群中对松异舟蛾的皮肤反应进行了研究。这是松林地区常见的一种病症，只有少数病例是由IgE介导的过敏机制引起的。这一事实与成人研究形成对比，在成人研究中这个比例要高得多。
