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他汀类药物对生物人工主动脉瓣退变进展的影响。

Effect of statins on the progression of bioprosthetic aortic valve degeneration.

作者信息

Antonini-Canterin Francesco, Zuppiroli Alfredo, Popescu Bogdan A, Granata Gianluca, Cervesato Eugenio, Piazza Rita, Pavan Daniela, Nicolosi Gian Luigi

机构信息

Unità Operativa di Cardiologia, A.R.C., Azienda Ospedaliera S. Maria degli Angeli, Pordenone, Italy.

出版信息

Am J Cardiol. 2003 Dec 15;92(12):1479-82. doi: 10.1016/j.amjcard.2003.08.066.

Abstract

To date, there is no proved medical therapy able to significantly reduce the degenerative process of biologic prosthetic aortic valves. It has recently been suggested that statins may reduce the progression of native aortic valve stenosis. We examined the effect of statin treatment on bioprosthetic aortic valve degeneration and found a beneficial effect of statins in slowing bioprosthetic degeneration.

摘要

迄今为止,尚无经证实的医学疗法能够显著减缓生物人工主动脉瓣的退变过程。最近有研究表明,他汀类药物可能会减缓天然主动脉瓣狭窄的进展。我们研究了他汀类药物治疗对生物人工主动脉瓣退变的影响,发现他汀类药物在减缓生物人工瓣膜退变方面具有有益作用。

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