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人类CD4+CD25+和CD4+CD25- T细胞之间基因表达谱的差异。

Difference in gene expression profiles between human CD4+CD25+ and CD4+CD25- T cells.

作者信息

Pati Nirupma, Ghosh Soumitra, Hessner Martin J, Khoo Huoy-Jii, Wang Xujing

机构信息

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College and Children's Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA.

出版信息

Ann N Y Acad Sci. 2003 Nov;1005:279-83. doi: 10.1196/annals.1288.043.

DOI:10.1196/annals.1288.043
PMID:14679076
Abstract

We studied the gene expression profiles of human CD4+CD25+ and CD4+CD25- T cells by using cDNA microarrays. Our preliminary results indicate that there are likely significant differences in the regulation of apoptosis, cell cycle, cytokine receptor, cell-cell interaction, and stress pathway genes between these two subtypes of T cells.

摘要

我们通过使用cDNA微阵列研究了人类CD4+CD25+和CD4+CD25- T细胞的基因表达谱。我们的初步结果表明，这两种T细胞亚型在细胞凋亡、细胞周期、细胞因子受体、细胞间相互作用和应激途径基因的调控方面可能存在显著差异。

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Difference in gene expression profiles between human CD4+CD25+ and CD4+CD25- T cells.人类CD4+CD25+和CD4+CD25- T细胞之间基因表达谱的差异。
Ann N Y Acad Sci. 2003 Nov;1005:279-83. doi: 10.1196/annals.1288.043.
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Utilization of a labeled tracking oligonucleotide for visualization and quality control of spotted 70-mer arrays.利用标记的追踪寡核苷酸对斑点70聚体阵列进行可视化和质量控制。
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