Wilson D A, Sullivan R M
Department of Psychology, University of Oklahoma, Norman 73019.
Brain Res. 1992 Oct 23;594(1):143-5. doi: 10.1016/0006-8993(92)91039-h.
Association of odor and reward during the early postnatal period modifies rat pup behavioral responses and olfactory bulb neural responses to subsequent presentations of that odor. Recent evidence has shown that olfactory bulb output neurons, mitral/tufted cells, receive convergent odor and reward inputs. The present report demonstrates that contiguous odor-reward pairings prevent mitral/tufted cell habituation to the odor that normally occurs to repeated odor-only stimulation. It is hypothesized that the maintenance of olfactory bulb responses to conditioned odors during training may allow for activation of long-term memory mechanisms.
出生后早期气味与奖赏的关联会改变幼鼠的行为反应以及嗅球对该气味后续呈现的神经反应。最近的证据表明，嗅球输出神经元，即僧帽/簇状细胞，会接收气味和奖赏的汇聚输入。本报告表明，连续的气味-奖赏配对可防止僧帽/簇状细胞对仅重复气味刺激时通常会出现的气味产生习惯化。据推测，训练期间嗅球对条件气味的反应维持可能会激活长期记忆机制。
