Sutherland Alan G, Alvarez Juan, Ding Weidong, Foreman K W, Kenny Cynthia Hess, Labthavikul Pornpen, Mosyak Lidia, Petersen Peter J, Rush Thomas S, Ruzin Alexey, Tsao Desiree H H, Wheless Karen L
Chemical and Screening Sciences, Wyeth Research, Pearl River, NY 10965, USA.
Org Biomol Chem. 2003 Dec 7;1(23):4138-40. doi: 10.1039/b312016c. Epub 2003 Oct 29.
Structural features of two weak inhibitors of the ZipA-FtsZ protein-protein interaction which were found to bind to overlapping but different areas of the key binding site were combined in one new series of carboxybiphenyl-indoles with improved inhibitory activity.
两种ZipA-FtsZ蛋白-蛋白相互作用的弱抑制剂的结构特征被发现可结合到关键结合位点的重叠但不同区域，将这些特征整合到一个新的羧基联苯-吲哚系列中，其抑制活性得到了提高。
Zotero 插件