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嗜盐嗜碱菌(嗜盐栖热菌)核糖体蛋白HS15和HSH基因的核苷酸序列:一个古菌特异性基因簇。

Nucleotide sequence of the genes for ribosomal proteins HS15 and HSH from Haloarcula marismortui: an archaeon-specific gene cluster.

作者信息

Arndt E, Steffens C

机构信息

Max-Planck-Institut für Molekulare Genetik, Abteilung Wittmann, Berlin, Germany.

出版信息

FEBS Lett. 1992 Dec 21;314(3):211-4. doi: 10.1016/0014-5793(92)81473-y.

Abstract

The nucleotide sequences of the genes for two ribosomal proteins, HS15 and HSH, from the archaeon Haloarcula marismortui, have been determined. The genes were found in a cluster together with another open reading frame with a probable regulatory function. HS15 and HSH have counterparts in eucarya. HS15 is significantly homologous to S19 from frog (Xenopus laevis). HSH is related to S37 from yeast (Saccharomyces cerevisiae) and S27 from fly (Drosophila melanogaster), as well as to other members of the S27 family. Eubacterial counterparts were not found, suggesting that these proteins are 'extra proteins' that are absent in eubacterial ribosomes.

摘要

已确定古菌嗜盐嗜碱菌(Haloarcula marismortui)中两种核糖体蛋白HS15和HSH的基因的核苷酸序列。这些基因与另一个具有可能调控功能的开放阅读框一起存在于一个基因簇中。HS15和HSH在真核生物中有对应物。HS15与青蛙(非洲爪蟾,Xenopus laevis)的S19显著同源。HSH与酵母(酿酒酵母,Saccharomyces cerevisiae)的S37、果蝇(黑腹果蝇,Drosophila melanogaster)的S27以及S27家族的其他成员相关。未发现真细菌的对应物,这表明这些蛋白质是真细菌核糖体中不存在的“额外蛋白质”。

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