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腹腔镜下肾细胞癌手术

Laparoscopic surgery for renal cell carcinoma.

作者信息

Hasan Waleed A, Abreu Sidney C, Gill Inderbir S

机构信息

Section of Laparoscopic and Minimally Invasive Surgery, Glickman Urological Institute, Cleveland Clinic Foundation, Ohio 44195, USA.

出版信息

Expert Rev Anticancer Ther. 2003 Dec;3(6):830-6. doi: 10.1586/14737140.3.6.830.

Abstract

New minimally invasive technologies are currently being applied to the management of renal cell carcinoma in an effort to decrease operative time, pain, morbidity and hospital stay. Foremost among these is the burgeoning role of laparoscopy in tumor destruction and complete in vivo resection. The primary modalities in clinical use today are laparoscopic radical nephrectomy, laparoscopic partial nephrectomy, laparoscopic renal cryoablation and laparoscopic radiofrequency ablation. Most initial reports include only highly selected patients with unifocal, small, exophytic, peripheral lesions away from the collecting system. As experience with these techniques increases, larger and more difficult lesions are being approached laparoscopically, with promising anecdotal results reported. Laparoscopic access to the kidney may be retroperitoneal or transperitoneal. Complete tumor destruction with maximal preservation of unaffected nephrons remains the goal. Herein, an update on laparoscopic surgery for renal cell carcinoma is presented. For each procedure, the current indications and contraindications, perioperative data, complications and oncological outcomes are described. In the future, it appears likely that laparoscopy will play a major role in the established treatment options for renal cell carcinoma, with open surgery being reserved for specific indications.

摘要

目前,新型微创技术正应用于肾细胞癌的治疗,旨在缩短手术时间、减轻疼痛、降低发病率并减少住院时间。其中,腹腔镜在肿瘤毁损和完整体内切除方面的作用日益凸显。当前临床应用的主要方式包括腹腔镜根治性肾切除术、腹腔镜部分肾切除术、腹腔镜肾冷冻消融术和腹腔镜射频消融术。大多数初步报告仅纳入了经过高度筛选的患者,这些患者的肿瘤为单灶性、体积小、外生性、位于外周且远离集合系统。随着对这些技术经验的增加,越来越大且难度更高的病变也开始通过腹腔镜进行处理,并有令人鼓舞的病例报告结果。腹腔镜进入肾脏的途径可以是经后腹腔或经腹腔。最大程度地保留未受影响的肾单位并实现肿瘤的完全毁损仍是目标。本文介绍了肾细胞癌腹腔镜手术的最新进展。对于每种手术,均描述了当前的适应证和禁忌证、围手术期数据、并发症及肿瘤学结局。未来,腹腔镜手术似乎很可能在肾细胞癌既定的治疗方案中发挥主要作用,而开放手术则保留用于特定适应证。

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Laparoscopic surgery for renal cell carcinoma.腹腔镜下肾细胞癌手术
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