Hirsch R D
Abteilung für Gerontopsychiatrie und Gerontopsychiatrisches Zentrum, Rheinische Kliniken Bonn.
Internist (Berl). 2003 Dec;44(12):1584-96. doi: 10.1007/s00108-003-1083-5.
Dementing illnesses present among the most frequent and most consequential psychiatric disorders in old age. They thus constitute a particular challenge for science politics and society as a whole. Knowledge about multifactorial etiological and pathological factors is still rather limited. By way of stratified diagnostic procedures various dementia disorders can be differentiated rather reliably. Anti-dementia drugs can enhance cognitive performance and temporarily slow down the progress of the most frequently occurring dementias (Alzheimer-dementia, vascular dementia). In the treatment of behavioral symptoms in dementia newly developed psychopharmological agents are of particular relevance. They constitute an important element of a multi-modal therapeutic strategy.
痴呆症是老年人群中最常见且后果最为严重的精神疾病之一。因此，它们对科学、政策和整个社会构成了特殊挑战。关于多因素病因和病理因素的知识仍然相当有限。通过分层诊断程序，可以较为可靠地区分各种痴呆症。抗痴呆药物可以提高认知能力，并暂时减缓最常见痴呆症（阿尔茨海默病性痴呆、血管性痴呆）的进展。在治疗痴呆症的行为症状方面，新开发的精神药物具有特别重要的意义。它们是多模式治疗策略的重要组成部分。
