Talbäck Mats, Stenbeck Magnus, Rosén Måns, Barlow Lotti, Glimelius Bengt
Centre for Epidemiology, The National Board of Health and Welfare, Stockholm, Sweden.
Acta Oncol. 2003;42(7):637-59. doi: 10.1080/02841860310013391.
This paper summarizes a comprehensive study of cancer survival in Sweden from 1960 to 1998. A total of 1021421 persons and 40 different cancer sites were included in the analyses. The main outcome measure is the relative survival rate (RSR) for different sites and follow-up times after diagnosis. The 10-year RSR for all sites combined has increased steadily-from 26.6% among men and 41.8% among women in the 1960s, to 44.6% (men) and 57.6% (women) in the 1990s. The expectation of life for a person diagnosed with cancer today is about 7 years longer than that of one diagnosed during the mid-1960s. About 3 years are gained due to changes in the relative distribution of various cancer types and about 4 years due to improved relative survival. During the 1990s substantial survival improvements were observed not only for uncommon types, such as testicular cancer, Hodgkin's lymphoma and some other haematologic malignancies, but also for cancer of the rectum, kidney and malignant melanoma. Survival for breast and cervical cancer also improved during the 1990s, but not that for pancreatic, liver or lung cancer.
本文总结了一项对1960年至1998年瑞典癌症生存率的全面研究。分析共纳入了1021421人以及40个不同的癌症部位。主要的结局指标是不同部位以及诊断后随访时间的相对生存率（RSR）。所有部位综合的10年相对生存率稳步上升——从20世纪60年代男性的26.6%和女性的41.8%，升至20世纪90年代的44.6%（男性）和57.6%（女性）。如今被诊断为癌症的人的预期寿命比20世纪60年代中期被诊断为癌症的人长约7年。由于各种癌症类型相对分布的变化，约增加了3年，由于相对生存率的提高，约增加了4年。在20世纪90年代，不仅在睾丸癌、霍奇金淋巴瘤和其他一些血液系统恶性肿瘤等罕见类型中观察到生存率有显著提高，在直肠癌、肾癌和恶性黑色素瘤中也观察到了生存率的显著提高。20世纪90年代乳腺癌和宫颈癌的生存率也有所提高，但胰腺癌、肝癌或肺癌的生存率没有提高。
