de Giorgi Vincenzo, Massi Daniela, Brunasso Giovanna, Salvini Camilla, Mastrolorenzo Antonio, Zuccati Giuliano, Carli Paolo
Department of Dermatology, University of Florence, Florence, Italy.
J Cutan Pathol. 2004 Feb;31(2):185-8. doi: 10.1111/j.0303-6987.2004.00153.x.
Multiple blue nevi have rarely been reported, and the majority of the lesions are located on the trunk and lower extremities. The blue nevus is a rare lesion on genital mucosa and may cause confusion in differential diagnosis with other pigmented lesions such as genital melanocytic macules, lentigo simplex, and malignant melanoma. Here, we describe an unusual patient who presented with a sudden onset in adulthood of multiple blue nevi on the glans penis. The epiluminescence examination revealed a substantially homogenous bluish pigmentation, which led us to favor a diagnosis of blue nevus, whereas not entirely excluding the possibility of a regressing melanoma or a metastatic melanoma. Because of the well-known diagnostic value of the blue hue in the diagnosis of malignancy by dermoscopy, a careful examination of these lesions should be made in order to minimize any risk of misclassification with melanoma.
多发性蓝色痣鲜有报道，大多数病损位于躯干和下肢。蓝色痣在生殖器黏膜上是一种罕见病损，可能会在与其他色素沉着性病变（如生殖器黑素细胞斑、单纯性雀斑样痣和恶性黑色素瘤）的鉴别诊断中造成混淆。在此，我们描述了一名不寻常的患者，其成年后龟头突然出现多发性蓝色痣。表皮透光检查显示色素沉着基本均匀呈蓝色，这使我们倾向于诊断为蓝色痣，尽管不能完全排除消退期黑色素瘤或转移性黑色素瘤的可能性。由于皮肤镜检查中蓝色调对恶性肿瘤诊断具有众所周知的价值，因此应仔细检查这些病损，以尽量降低与黑色素瘤误诊的风险。
