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[生殖器黏膜色素沉着病变]

[Pigmented lesions of the genital mucosa].

作者信息

Hengge U R, Meurer M

机构信息

Klinik für Dermatologie, Heinrich-Heine-Universität, Düsseldorf.

出版信息

Hautarzt. 2005 Jun;56(6):540-9. doi: 10.1007/s00105-005-0961-2.

Abstract

Pigmented lesions of the genital mucosa are more frequent in women than in men. They represent a spectrum of different benign entities. A biopsy is always recommended when the diagnosis cannot be made with certainty on clinical examination and dermatoscopy. Differential diagnostic considerations include melanocytic nevi, blue nevi and syndromes featuring lentigines. Malignant melanomas of the penis and vulva are uncommon tumors which usually appear in elderly patients. They frequently present as painless palpable nodules at routine examination. The treatment consists of excision with histological control of the margins. An aggressive surgical approach has not been shown to prolong the poor 5-year survival. Cooperation with gynecologists and urologists is essential for the optimal management of such patients.

摘要

女性生殖黏膜色素沉着病变比男性更为常见。它们代表了一系列不同的良性病变。当临床检查和皮肤镜检查不能明确诊断时,始终建议进行活检。鉴别诊断需考虑黑素细胞痣、蓝痣以及伴有雀斑样痣的综合征。阴茎和外阴恶性黑色素瘤是罕见肿瘤,通常发生于老年患者。在常规检查中,它们常表现为无痛性可触及结节。治疗方法为切除并对切缘进行组织学检查。积极的手术方法并未显示能延长较差的5年生存率。与妇科医生和泌尿科医生合作对于此类患者的最佳管理至关重要。

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