Ho K K, Otridge B W, Vandenberg E, Powell F C
Regional Centre of Dermatology, Mater Misericordiae Hospital, Dublin, Ireland.
J Am Acad Dermatol. 1992 Nov;27(5 Pt 2):804-8. doi: 10.1016/0190-9622(92)70252-b.
A patient with long-standing, well-controlled polycythemia rubra vera developed recurrent episodes of bullous pyoderma gangrenosum followed by the transformation of his hematologic disease into a rapidly progressive acute myeloid leukemia. This case, together with previously described patients, indicates that the appearance of bullous pyoderma gangrenosum in a patient with polycythemia rubra vera is often of ominous prognostic significance.