Duguid C M, O'Loughlin S, Otridge B, Powell F C
Department of Dermatology, Mater Misericordiae Hospital, Dublin, Ireland.
Australas J Dermatol. 1993;34(1):17-22. doi: 10.1111/j.1440-0960.1993.tb00841.x.
Pyoderma Gangrenosum (PG) is often associated with an underlying disease. PG as a paraneoplastic disease is illustrated by the presentation of four patients with malignancy of myeloproliferative origin and PG. An associated malignancy is found in approximately 7% of patients with PG, most commonly haematologic in nature and in particular leukaemia. Clinically the PG is often of the superficial bullous variant and is associated with a poor prognosis.
坏疽性脓皮病(PG)常与潜在疾病相关。4例起源于骨髓增殖性疾病并患有PG的恶性肿瘤患者的表现说明了PG作为一种副肿瘤性疾病。在约7%的PG患者中发现相关恶性肿瘤,最常见的是血液系统恶性肿瘤,尤其是白血病。临床上,PG通常为浅表大疱型,预后较差。