Zhivotovsky Lev A, Underhill Peter A, Cinnioğlu Cengiz, Kayser Manfred, Morar Bharti, Kivisild Toomas, Scozzari Rosaria, Cruciani Fulvio, Destro-Bisol Giovanni, Spedini Gabriella, Chambers Geoffrey K, Herrera Rene J, Yong Kiau Kiun, Gresham David, Tournev Ivailo, Feldman Marcus W, Kalaydjieva Luba
N. I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Am J Hum Genet. 2004 Jan;74(1):50-61. doi: 10.1086/380911. Epub 2003 Dec 19.
We estimate an effective mutation rate at an average Y chromosome short-tandem repeat locus as 6.9x10-4 per 25 years, with a standard deviation across loci of 5.7x10-4, using data on microsatellite variation within Y chromosome haplogroups defined by unique-event polymorphisms in populations with documented short-term histories, as well as comparative data on worldwide populations at both the Y chromosome and various autosomal loci. This value is used to estimate the times of the African Bantu expansion, the divergence of Polynesian populations (the Maoris, Cook Islanders, and Samoans), and the origin of Gypsy populations from Bulgaria.
我们利用有近期历史记录人群中由独特事件多态性定义的Y染色体单倍群内微卫星变异的数据,以及全球人群在Y染色体和多个常染色体位点的比较数据,估计Y染色体短串联重复序列平均位点的有效突变率为每25年6.9×10⁻⁴,各基因座的标准差为5.7×10⁻⁴。该值用于估计非洲班图人的扩张时间、波利尼西亚人群(毛利人、库克岛民和萨摩亚人)的分化时间以及保加利亚吉普赛人群的起源时间。