Marshall Peter J, Bar-Haim Yair, Fox Nathan A
Department of Human Development, University of Maryland, 3304 Benjamin Building, College Park, MD 20742, USA.
Int J Psychophysiol. 2004 Jan;51(2):135-41. doi: 10.1016/j.ijpsycho.2003.08.004.
The development of P50 suppression in the auditory event-related potential was examined in 32 participants aged 7-13 years and the relation of P50 suppression to individual differences in social withdrawal was investigated. Auditory click pairs were presented binaurally and the amplitude of the P50 component was measured for the two clicks. Across the whole sample, P50 amplitude to the second click was significantly smaller than P50 amplitude to the first click, although around one third of participants showed augmentation of the P50 to the second click. For the children who showed P50 suppression, the magnitude of P50 suppression increased with age and reached adult levels in the oldest participants. P50 suppression did not vary with the extent of social withdrawal behaviors.
研究了32名7至13岁参与者听觉事件相关电位中P50抑制的发展情况，并调查了P50抑制与社交退缩个体差异之间的关系。双耳呈现听觉点击对，并测量两次点击时P50成分的幅度。在整个样本中，第二次点击时的P50幅度明显小于第一次点击时的P50幅度，尽管约三分之一的参与者第二次点击时P50出现增强。对于表现出P50抑制的儿童，P50抑制的程度随年龄增加，并在年龄最大的参与者中达到成人水平。P50抑制与社交退缩行为的程度无关。
