Yang Dong Hoon, Myung Seung-Jae, Chang Hye-Sook, Song Jin Woo, Yang Suk-Kyun, Lee Gin Hyug, Jung Hwoon-Yong, Hong Weon-Seon, Kim Jin-Ho, Min Young Il, Kim Hee Cheol, Huh Jooryung, Oh Heung-Bum
Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Songpa-gu, Seoul, Korea.
Korean J Gastroenterol. 2003 Dec;42(6):527-32.
Enteropathy-associated T-cell lymphoma (EATL) is an unusual primary gastrointestinal lymphoma, particularly associated with celiac sprue. This tumor usually affects the jejunum and grossly presents as multiple circumferential ulcers without the formation of definite tumor masses. Moreover, mesenteric lymph nodes are commonly involved. The patients have typically suffered from abdominal pain, diarrhea, or weight loss whereas some patients may manifest with nonspecific symptoms for a period of years or an acute emergency of perforation, obstruction, or hemorrhage. The clinical course of EATL is very unfavorable and the prognosis is poor. Both celiac sprue and EATL are very rare diseases in Asia, except India and Middle East. We report a 60-year-old male diagnosed as having EATL after segmental small bowel resection, who presented with recurrent gastrointestinal bleeding.
肠病相关T细胞淋巴瘤(EATL)是一种罕见的原发性胃肠道淋巴瘤,尤其与乳糜泻相关。这种肿瘤通常累及空肠,大体表现为多个环形溃疡,无明确肿瘤肿块形成。此外,肠系膜淋巴结常受累。患者通常有腹痛、腹泻或体重减轻症状,而一些患者可能在数年时间内表现为非特异性症状,或出现穿孔、梗阻或出血等急性急症。EATL的临床病程非常不利,预后很差。除印度和中东地区外,乳糜泻和EATL在亚洲都是非常罕见的疾病。我们报告一例60岁男性,在节段性小肠切除术后被诊断为EATL,该患者表现为反复胃肠道出血。