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本文引用的文献

1
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Environ Health Perspect. 2004 Jan;112(1):94-104. doi: 10.1289/ehp.6264.
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Methodologic and statistical approaches to studying human fertility and environmental exposure.研究人类生育能力与环境暴露的方法学和统计学方法。
Environ Health Perspect. 2004 Jan;112(1):87-93. doi: 10.1289/ehp.6263.
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Prospective pregnancy study designs for assessing reproductive and developmental toxicants.用于评估生殖和发育毒性物质的前瞻性妊娠研究设计。
Environ Health Perspect. 2004 Jan;112(1):79-86. doi: 10.1289/ehp.6262.
5
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6
Endocrine programming and fetal origins of adult disease.内分泌编程与成人疾病的胎儿起源
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7
Impact of Endocrine Disruptors on Brain Development and Behaviour. Proceedings of a conference. 15-20 September 2001, Sicily, Italy.内分泌干扰物对大脑发育和行为的影响。一次会议的会议记录。2001年9月15日至20日,意大利西西里岛
Environ Health Perspect. 2002 Jun;110 Suppl 3(Suppl 3):335-449.
8
Putative effects of endocrine disrupters on pubertal development in the human.内分泌干扰物对人类青春期发育的潜在影响。
Best Pract Res Clin Endocrinol Metab. 2002 Mar;16(1):105-21. doi: 10.1053/beem.2002.0184.
9
Fetal, infant, and childhood growth are predictors of coronary heart disease, diabetes, and hypertension in adult men and women.胎儿期、婴儿期及儿童期的生长发育情况是成年男性和女性患冠心病、糖尿病及高血压的预测指标。
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10
Fetal origins of coronary heart disease.冠心病的胎儿起源
BMJ. 1995 Jul 15;311(6998):171-4. doi: 10.1136/bmj.311.6998.171.

我们一生一次的机会。

Our once-in-a-lifetime opportunity.

作者信息

Chapin Robert E, Buck Germaine M

机构信息

Reproductive and Developmental Toxicology Group, Pfizer Global Research and Development, Safety Sciences, Eastern Point Road, MS 8274-1336, Groton, CT 06340, USA.

出版信息

Environ Health Perspect. 2004 Jan;112(1):67-8. doi: 10.1289/ehp.6733.

DOI:10.1289/ehp.6733
PMID:14698933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1241799/
Abstract

Longitudinal studies of the determinants of children's health are complex, costly, infrequent, and incredibly valuable. It has become clear in recent years that the periconceptional environment plays a surprisingly large role in the health of the resulting child. This short introduction to this mini-monograph briefly recaps the articles included herein and reminds us that adequate forethought and planning will result in a study that could shed new light on the earliest determinants of children's health and thereby fill critical data gaps.

摘要

对儿童健康决定因素的纵向研究复杂、成本高、开展频率低,但却极具价值。近年来已经很清楚的是,受孕前后的环境对所生育孩子的健康起着惊人的巨大作用。本专题论文集的简短引言简要回顾了其中包含的文章,并提醒我们,充分的预先思考和规划将带来一项能够为儿童健康的最早决定因素提供新见解从而填补关键数据空白的研究。