Chapin Robert E, Buck Germaine M
Reproductive and Developmental Toxicology Group, Pfizer Global Research and Development, Safety Sciences, Eastern Point Road, MS 8274-1336, Groton, CT 06340, USA.
Environ Health Perspect. 2004 Jan;112(1):67-8. doi: 10.1289/ehp.6733.
Longitudinal studies of the determinants of children's health are complex, costly, infrequent, and incredibly valuable. It has become clear in recent years that the periconceptional environment plays a surprisingly large role in the health of the resulting child. This short introduction to this mini-monograph briefly recaps the articles included herein and reminds us that adequate forethought and planning will result in a study that could shed new light on the earliest determinants of children's health and thereby fill critical data gaps.
对儿童健康决定因素的纵向研究复杂、成本高、开展频率低,但却极具价值。近年来已经很清楚的是,受孕前后的环境对所生育孩子的健康起着惊人的巨大作用。本专题论文集的简短引言简要回顾了其中包含的文章,并提醒我们,充分的预先思考和规划将带来一项能够为儿童健康的最早决定因素提供新见解从而填补关键数据空白的研究。