Coope J, Marsh J
Bollington Medical Centre, Cheshire, UK.
Maturitas. 1992 Oct;15(2):151-8. doi: 10.1016/0378-5122(92)90249-4.
In order to increase awareness of strategies to prevent osteoporosis and heart disease we designed a clinic offering education and screening to all women aged 40-60 years on our practice list of 8600 patients, starting in January 1988. Screening and supervision of HRT users occurred at a weekly clinic run by the doctor and nurse. Audit in August 1991 showed that there were 260 present users of HRT (20%) of our population of 1322 women aged 40-60 years. Seventy-eight percent had taken HRT for over a year and 15% for more than 5 years. Ex-users totalled 117, of whom 52% had taken HRT for over a year and 14% for over 5 years. Examination of the clinic registers and responses to postal questionnaires showed that 681 (51.5%) of patients attended the health education clinic. Of the clinic attenders, 25% took HRT compared with 10.8% of non-attenders. Compliance with long-term therapy measured by audit of repeat prescriptions varied between 84% and 92% over a period of 5 years. Reasons for stopping treatment were anxiety over possible side-effects, especially breast cancer and dislike of bleeding.
为了提高对预防骨质疏松症和心脏病策略的认识，我们于1988年1月开始设立了一家诊所，为我们8600名患者名单中40至60岁的所有女性提供教育和筛查服务。激素替代疗法（HRT）使用者的筛查和监督在由医生和护士每周开设的诊所进行。1991年8月的审计显示，在我们1322名40至60岁的女性人群中，有260名目前正在使用HRT（占20%）。78%的人使用HRT超过一年，15%的人使用超过五年。曾经使用过HRT的人共有117名，其中52%使用HRT超过一年，14%使用超过五年。对诊所登记记录和邮寄问卷调查回复的检查显示，681名（51.5%）患者参加了健康教育诊所。在参加诊所的人中，25%使用HRT，而未参加者中这一比例为10.8%。通过重复处方审计衡量的长期治疗依从性在5年期间为84%至92%。停止治疗的原因是对可能的副作用，尤其是乳腺癌的担忧，以及不喜欢出血。
